DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and slc-17.9

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001379067.1	Gene:	slc-17.9 / 181189	WormBaseID:	WBGene00011643	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	478	Identity:	115/478 - (24%)
Similarity:	195/478 - (40%)	Gaps:	58/478 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPNFP---------------EYDWTEAEKSYIFS 67
            :.|:.|....:.||..|:..|:|.|.....||...|               ::.|:..::..|:|
Worm    25 SFLLCLCFVALAIGTSNISQSMVCMVKKPDTNYTCPLAEPEVEAIPCNHPKQFAWSSIQQGLIYS 89

  Fly    68 SFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYCGIRVVMGLAQGL 132
            ...:| .|...|.|:...|...|..:...:....|.:|:.|:..| ..:.....:||:.|....|
Worm    90 GQNFG-SLFMVITGWQADRLNGKWTIVAAMAFIIVSNAVLPISAG-ASFALVFFLRVLTGFGDAL 152

  Fly   133 VFPCIHHHLAKWSPPAER-NRLGALSHTGMECGNVSAMFLSGMI-----AKSAIGWPGISYVSAG 191
            :.|.....:.:|.||.|| :.||.:: :|.:.|.:..:.:.|.:     :|...|||.|.|:|:.
Worm   153 LSPASSSLITRWFPPKERPSALGIVT-SGRQIGTLIILPIGGWLCGSDGSKFLGGWPAIFYLSSV 216

  Fly   192 LAFAWCAIWFVFAADNAVESRYITQEELHYIESSL------KHNEDYHKTVIPVPWMAIWTSAPF 250
            :|.|...||.||:||...:...|:..|..||...:      |.|...:     .||.||:||...
Worm   217 VAAAVLVIWVVFSADKPSKHLCISHNEEAYINRKIEEENIGKRNNRKN-----TPWKAIFTSKQV 276

  Fly   251 LALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGN 315
            ........|..:.|..:...:|.:.:.||.:....|...||||...:::...:...:|..|.|..
Worm   277 WVAVAALVCHEFPLVIMLQFLPKFFSDVLGLSNTVNGLVSALPMAILFLSKCLSASLASYLTANG 341

  Fly   316 RLSLTALRKTFNSLAFWIPCATLIGIGF---LDQEQKNLAIALMTISVGVNSGATIGSSLNT--- 374
            .|..|...|.||.:|       .:|:|.   ......||..|:..|.:...:.|..|  |:|
Worm   342 YLRKTQSCKIFNFIA-------SLGLGICIAATPLMSNLQHAIWAIIILCLANAFAG--LHTPGV 397

  Fly   375 ----IDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVY 435
                :.|:|..:.|:.|:.....:...|...|::..|: ...::.||.|||.|:|.:..:....:
Worm   398 LTAIVQLAPAFSGIITGLAFAVASCFSIFNKLLISQIL-RTGSKHEWTIVFEISAFVAILPTIFF 461

  Fly   436 LYFGTAVSQPWDAEDYLTVKVPE 458
            ..:|:|....|.:.   .|.||:
Worm   462 TLWGSAERTEWASN---RVSVPK 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	112/468 (24%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	98/405 (24%)
slc-17.9	NP_001379067.1	2A0114euk	5..474	CDD:129972	112/466 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930