DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and slc-17.8

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001023848.1	Gene:	slc-17.8 / 179234	WormBaseID:	WBGene00017798	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	458	Identity:	116/458 - (25%)
Similarity:	200/458 - (43%)	Gaps:	42/458 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT--NPNFPE-----YDWTEAEKSYIFSSFFW 71
            |.:.::::......|.:...|:|:::|.|.|:..|  |..:||     .||:..|:.||||:|..
Worm    53 RFMTSIMLCFCFGCVHLMNSNMGMAIVCMVNSSATYDNETYPENAAPLLDWSSDEQGYIFSAFNA 117

  Fly    72 GYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQA----YCGI--RVVMGLAQ 130
            |.::..|.|| :..:|..|.::...|.::.:.:...|       |.|    |..|  |.::|.|.
Worm   118 GLLVMLFTGG-MADKFNAKYMILVSVAIASLANFTLP-------WMAPISVYWAIFSRFLVGFAD 174

  Fly   131 GLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAI---GWPGISYVSAGL 192
            .|:.|.::..:.:|.|.:||:....|:..|.:.|.:..:..:|.:.....   |||.|.|:|..:
Worm   175 ALLQPAMNSLITRWFPTSERSYALGLATGGRQIGTLIIIPAAGALCSQTEIFGGWPSIFYLSGFI 239

  Fly   193 AFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHK--TVIPVPWMAIWTSAPFLALTL 255
            ...:...:....||...:...|:..||.:|..| ..:||..|  |...|||..|..|....|..:
Worm   240 GVLFIFSYIFLGADKPSKQSCISDNELKFITIS-NQSEDVGKKRTERKVPWKNILKSGAVWASVI 303

  Fly   256 TRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLT 320
            :..|..:.|.||...:|:|::.|.......|...||||.:::|........:...|.........
Worm   304 SLVCHEFPLMTLIMFLPSYLHDVHHYHSTENGILSALPTVSLWFAKIGSSYLNTWLQKNTTWKKD 368

  Fly   321 ALRKTFNSLAFWIPCATLIGIG-------FLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLS 378
            .:.|..||:.       .||:|       |||.|...:|:..:.:|:......|.|..|..:.::
Worm   369 TICKVLNSIG-------SIGLGVFLLAATFLDNEHAWMAVLFLCLSMASAGLHTPGCQLALVSVA 426

  Fly   379 PNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVS 443
            |.::..:.|.....|.|..|:.|:|..:|| :|...|||.:||.|:.|:......::..:|:...
Worm   427 PAYSGAVTGFTFFFVAVSGIIHPIITKMIV-KDRTAAEWNLVFYISTVIAIFPIIIFNVWGSTEV 490

  Fly   444 QPW 446
            |.|
Worm   491 QWW 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	116/458 (25%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	103/406 (25%)
slc-17.8	NP_001023848.1	MFS_SLC17	57..486	CDD:340876	112/445 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020