Protein Alignment CG12490 and eat-4

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_499023.3
• Gene: eat-4 / 176291
• WormBaseID: WBGene00001135
• Length: 576
• Species: Caenorhabditis elegans
• Alignment Length: 471
• Identity: 132/471 - (28%)
• Similarity: 218/471 - (46%)
• Gaps: 27/471 - (5%)

  Fly    14 RHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNP----NFPEYDWTEAEKSYIFSSFFWGYI 74
            |.:.|:|..:.....|..|.|.|.:...|.. ..|:|    :..|::||..|.|.:.||:|:||:
 Worm    69 RWLLAILANMGFMISFGIRCNFGAAKTHMYK-NYTDPYGKVHMHEFNWTIDELSVMESSYFYGYL 132

  Fly    75 LTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAY--CGIRVVMGLAQGLVFPCI 137
            :||...|:|..:|....:..:|:.|....:.|.|  .||.....|  ..|::..||.||:.:|.:
 Worm   133 VTQIPAGFLAAKFPPNKLFGFGIGVGAFLNILLP--YGFKVKSDYLVAFIQITQGLVQGVCYPAM 195

  Fly   138 HHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFAWCAIWFV 202
            |.....|:||.||::|...:.||...|.|..:.||..:. |.:.|....|:.......|..:||.
 Worm   196 HGVWRYWAPPMERSKLATTAFTGSYAGAVLGLPLSAFLV-SYVSWAAPFYLYGVCGVIWAILWFC 259

  Fly   203 FAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAIWTSAPFLALTLTRCCATWGLSTL 267
            ...:.......|:|||..:||.::.|..:.|.|:..:||.||.||.|..|:.:.....:|....|
 Worm   260 VTFEKPAFHPTISQEEKIFIEDAIGHVSNTHPTIRSIPWKAIVTSKPVWAIIVANFARSWTFYLL 324

  Fly   268 QAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLI---IADVLLAGNRLSLTALRKTFNSL 329
            .....|||...|.|.:..:...:|:|.|   :|..|.|:   :||.|.:...||.||:||.||..
 Worm   325 LQNQLTYMKEALGMKIADSGLLAAIPHL---VMGCVVLMGGQLADYLRSNKILSTTAVRKIFNCG 386

  Fly   330 AFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGILNTAVT 394
            .|....|.::.:.:...:  ..||..:..:||::..|..|.::|.:|::|.:|:||||..|...|
 Worm   387 GFGGEAAFMLIVAYTTSD--TTAIMALIAAVGMSGFAISGFNVNHLDIAPRYAAILMGFSNGIGT 449

  Fly   395 VVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPW----DAEDYLTVK 455
            :..:..|.:.......  ::..|..||::|:::.|.|.:.|..:.:...|.|    :.|::..
 Worm   450 LAGLTCPFVTEAFTAH--SKHGWTSVFLLASLIHFTGVTFYAVYASGELQEWAEPKEEEEWSN-- 510

  Fly   456 VPELAKVPAIHEAGKG 471
             .||.....|:..|.|
 Worm   511 -KELVNKTGINGTGYG 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	123/429 (29%)
eat-4	NP_499023.3	MFS_SLC17A6_7_8_VGluT	73..492	CDD:340940	123/429 (29%)