Protein Alignment CG12490 and mfsc-1

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001254320.1
• Gene: mfsc-1 / 174820
• WormBaseID: WBGene00012085
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 117/532 - (21%)
• Similarity: 205/532 - (38%)
• Gaps: 109/532 - (20%)

  Fly     2 TAETNKGPVLG--MRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAE-----TTNPNFPEYDWTE 59
            ||:|....:.|  .|.|..:||.|.:|:::...|....:||.|.:.:     :.|....:..:|.
 Worm    20 TAQTRYISLFGTRTRFVIMVLILLCLTSIWSNILAFNFAVVCMDDDDSEMGASLNGTARKTHFTS 84

  Fly    60 AEKS-----YIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGV-FVSGVCSALTPLFIGFGGWQA 118
            .:.|     ...::....:.:.|.:|     ..|:::| |.|: .:|.|.:.|.||.|.. |:..
 Worm    85 TQNSLAMAIVAIAALLGNFPIVQLVG-----MVGIRTV-FAGLGILSAVSTLLIPLSIRM-GFYY 142

  Fly   119 YCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWP 183
            :..:|.:.|.|....||.|....||||...:                 :.:|:|.::|...:. |
 Worm   143 FLAVRFLQGFAFAANFPVIGSFCAKWSYFKQ-----------------NGLFVSSLVAYVQLS-P 189

  Fly   184 GISYVSAGL---AFAWCAIWFVFAADNAVESRYITQEELHYIESSLKH----NEDYHKTVI---- 237
            .|:..::|.   ||.|.:|   |.|..||.........|.|..|..||    |.:..|..|
 Worm   190 AITMPASGALCSAFKWPSI---FYAHGAVSLLLFVTYALFYRNSPQKHPFVGNVELKKISIGKIA 251

  Fly   238 ------------------PVPWMAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMK 284
                              |..| |:|.:    |:....|.....|.:     |.|::.||...:.
 Worm   252 AVDKRALKKVPYGPILKTPAIW-AVWVA----AIGNFTCVNMMFLFS-----PIYLSKVLGFPVH 306

  Fly   285 SNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLS-LTALR-----KTFNSLAFWIPCATLIGIGF 343
            |....:|:|         .:|..:..|:.|.... ||.|.     :.||:|||......|..:.|
 Worm   307 STGITAAIP---------PFLQFSSKLICGAASDRLTCLSEGVKFRLFNTLAFVGSAGFLCVLAF 362

  Fly   344 L-DQEQKNLAIALMTISVGVNSGATIGSSLNTID-LSPNHASILMGILNTAVTVVPIVTPLIVGV 406
            : |:.::|..|.|...:..:  |||.|....... ||..::..:.|.::..:|:..::.|..|..
 Worm   363 MGDEHKRNNMIVLGCAAAML--GATTGGFFKAGPVLSKQYSHFVTGNISLGITITMLIVPFFVNA 425

  Fly   407 IVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPWDAEDYLTVKVPELAKVPAIHEAGKG 471
            :. .::.:.||:.||:|...:..:.|..::.|.......|.::.:  .:...:|.....|....|
 Worm   426 LT-PNNTQEEWKYVFLITGAVMVITNIFFVIFVRGDPCEWTSDSF--HRASSVADFEQHHIRNTG 487

  Fly   472 I-------DDLP 476
            |       :|:|
 Worm   488 ISTISHNVEDVP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	103/468 (22%)
mfsc-1	NP_001254320.1	MFS	56..456	CDD:475125	98/449 (22%)