DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	452	Identity:	122/452 - (26%)
Similarity:	208/452 - (46%)	Gaps:	28/452 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LLIFLNITTVFIGRLNVGVSVVAMTNAETTNPNF--------------PEYDWTEAEKSYIFSSF 69
            ||.|.|| .:...|:.:.:::|||.| :|..|:.              |.:.|:...:..|.||.
  Rat    23 LLHFCNI-VIMAQRVCLNLTMVAMVN-KTEPPHLSNKSVAEMLDNVKNPVHSWSLDIQGLILSSV 85

  Fly    70 FWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFG-GWQAYCGIRVVMGLAQGLV 133
            |.|.::.|...|||...:.:|.::...:|:|.|.|.|.|.....| .....|  ||:.|:|||.|
  Rat    86 FLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIPPAAQVGAALVIVC--RVLQGIAQGAV 148

  Fly   134 FPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFAWCA 198
            ....|....||:||.||.||.:::.:|...|...|:.:||.|. ..:|||.:.|:...:......
  Rat   149 STGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFIC-DLLGWPMVFYIFGIVGCVLSL 212

  Fly   199 IWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAIWTSAPFLALTLTRCCATWG 263
            .||:...|:.....|::..|..||.|||.  :..|.....:|..|:..|.|..|:.|......|.
  Rat   213 FWFILFFDDPNNHPYMSSSEKDYITSSLM--QQVHSGRQSLPIKAMLKSLPLWAIILNSFAFIWS 275

  Fly   264 LSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFNS 328
            .:.|....||:::..|.::::.|...|:||:|..:|...|...::|.||:....|:.|:||.|.:
  Rat   276 NNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKIFSVVAVRKLFTT 340

  Fly   329 LAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGILNTAV 393
            |..:.|...::.:.:|.....:..| .:|::....|.:..|..:|.:|::|.:...|..:  ||:
  Rat   341 LGIFCPVIFVVCLLYLSYNFYSTVI-FLTLANSTLSFSFCGQLINALDIAPRYYGFLKAV--TAL 402

  Fly   394 TVV--PIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPWDAEDYLT 453
            ..:  .:::..:.|:|:::|...| |...|.:.|.:.....:.||.|.....|.|..|...|
  Rat   403 IGIFGGLISSTLAGLILNQDPEYA-WHKNFFLMAGINVTCLAFYLLFAKGDIQDWAKETKTT 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	120/447 (27%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	104/386 (27%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	122/452 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910