Protein Alignment CG12490 and SLC17A3

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 137/472 - (29%)
• Similarity: 223/472 - (47%)
• Gaps: 50/472 - (10%)

  Fly    16 VQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNP----------------------------NF 52
            :..:|.|.|.||: ...:.:.:::|||.|  :|:|                            ..
Human    41 IALVLHFCNFTTI-AQNVIMNITMVAMVN--STSPQSQLNDSSEVLPVDSFGGLSKAPKSLPAKA 102

  Fly    53 PEYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQ 117
            |.|||:...:..||.:..:|.|||....|||..|.|.|.|:...:|.:...:...||...|
Human   103 PVYDWSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLTLCIPLATDF---- 163

  Fly   118 AYCGI------RVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIA 176
               ||      |:|.||:|..:.........||.||.||:||.:::.:||..|..:|:.:.|.|:
Human   164 ---GIVLLIVTRIVQGLSQSSILGGQFAIWEKWGPPQERSRLCSIALSGMLLGCFTAILIGGFIS 225

  Fly   177 KSAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPVPW 241
            :: :|||.:.|:..|:....|.:|||...|:.|...:|:..|..||.||||......|.  |:|.
Human   226 ET-LGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISSLKQQVGSSKQ--PLPI 287

  Fly   242 MAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLI 306
            .|:..|.|..::.|......|.:||:...||||::.|..::::.|...|||||:..|::..|...
Human   288 KAMLRSLPIWSICLGCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGLLSALPFIVAWVIGMVGGY 352

  Fly   307 IADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSS 371
            :||.||. .:..|..:||....|......|.::.:.:|:..... |.||:|:|.|:::....|..
Human   353 LADFLLT-KKFRLITVRKIATILGSLPSSALIVSLPYLNSGYIT-ATALLTLSCGLSTLCQSGIY 415

  Fly   372 LNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYL 436
            :|.:|::|.::|.|||......::.|::.|.:.|.::.:|.... |:.||.:...:..:|...||
Human   416 INVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLLSQDPEFG-WRNVFFLLFAVNLLGLLFYL 479

  Fly   437 YFGTAVSQPWDAEDYLT 453
            .||.|..|.|..|..||
Human   480 IFGEADVQEWAKERKLT 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	129/454 (28%)
SLC17A3	NP_001091956.1	MFS_SLC17	42..482	CDD:340876	129/455 (28%)