Protein Alignment CG12490 and SLC17A2

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: XP_054209984.1
• Gene: SLC17A2 / 10246
• HGNCID: 10930
• Length: 487
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 127/493 - (25%)
• Similarity: 226/493 - (45%)
• Gaps: 53/493 - (10%)

  Fly     5 TNKGP-VLGMRHVQALLIFLNITTVFIGRLNVGVSVVAM---------TNAETTNP--------- 50
            |.||| ...:|:..||::..:..|:...|:::.::::||         :||.|..|
Human     7 TRKGPDFCSLRYGLALIMHFSNFTMITQRVSLSIAIIAMVNTTQQQGLSNASTEGPVADAFNNSS 71

  Fly    51 -NFPEYD-------WTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALT 107
             :..|:|       |:...:..||||..:|.|||....|||...||.|.::..|:.:|.:.:..|
Human    72 ISIKEFDTKASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFT 136

  Fly   108 PLFIGFGGWQAYCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLS 172
            ||...||...... :|.|.|:|||:.:.......|||:||.||::|..::.:|...|:...:.:.
Human   137 PLAADFGVILVIM-VRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCVG 200

  Fly   173 GMIAKSAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVI 237
            |:|:: |:.||.|.|:........|.:||....|:.:....|:..|..:|.|||..........:
Human   201 GLISQ-ALSWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCISVREKEHILSSLAQQPSSPGRAV 264

  Fly   238 PVPWMAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSY 302
            |:  .|:.|..|..|:.|......|..:.:...:|||::.:|.::::.:...|:|||:|....:.
Human   265 PI--KAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVNIRDSGVLSSLPFIAAASCTI 327

  Fly   303 VYLIIADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGAT 367
            :...:||.||:.|.|.|..:||.|:||...:|....:.:.|:..... :.|.|:.:..|.::...
Human   328 LGGQLADFLLSRNLLRLITVRKLFSSLGLLLPSICAVALPFVASSYV-ITIILLILIPGTSNLCD 391

  Fly   368 IGSSLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGN 432
            .|..:||:|::|.:||.||||......:..|::....|.::.:             ..:|..||.
Human   392 SGFIINTLDIAPRYASFLMGISRGFGLIAGIISSTATGFLISQ-------------VGILSLVGG 443

  Fly   433 SVYLYFGTAVSQPW------DAEDYLTVKVPELAKVPA 464
            ..:.....:....|      |.:::.|  .|:...:||
Human   444 MSFSCLLQSTCLAWSFTSRLDKQNFKT--GPKRGPLPA 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	116/446 (26%)
SLC17A2	XP_054209984.1	MFS_SLC17	21..434	CDD:340876	113/417 (27%)