Protein Alignment CG12490 and slc17a8

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: XP_002936892.1
• Gene: slc17a8 / 100489470
• XenbaseID: XB-GENE-988965
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 442
• Identity: 140/442 - (31%)
• Similarity: 218/442 - (49%)
• Gaps: 16/442 - (3%)

  Fly    14 RHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT----NPNF--PEYDWTEAEKSYIFSSFFWG 72
            |::.|::..|.....|..|.|:||::|.|.|..|.    .|..  .:::|.......|..|||||
 Frog    75 RYIIAMMSGLGFCISFGIRCNLGVAIVEMVNNNTVYVDGKPEMQKAQFNWDPETVGLIHGSFFWG 139

  Fly    73 YILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTP--LFIGFGGWQAYCGIRVVMGLAQGLVFP 135
            ||:||..||::..:.....|....:|::.:.:.|.|  ..:.||   ....:||:.||.:|:.:|
 Frog   140 YIITQIPGGFIANKLAANRVFGAAIFLTSILNMLIPSAARVHFG---CVISVRVLQGLVEGVTYP 201

  Fly   136 CIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFAWCAIW 200
            ..|...:||:||.||:||...|..|...|.|.||.|:|::.: .||||.:.|:.......|...|
 Frog   202 ACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGVLVQ-YIGWPSVFYIYGVFGMCWYVFW 265

  Fly   201 FVFAADNAVESRYITQEELHYIESSLKHNEDYHKT-VIPVPWMAIWTSAPFLALTLTRCCATWGL 264
            .:.|.::......||.||..|||:|:....:...| ....||...:||.|..|:.:...|.:|..
 Frog   266 LLHATESPAAHPSITFEERTYIETSIGEGSNLVTTGKFKTPWKKFFTSMPVYAIIVANFCRSWTF 330

  Fly   265 STLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFNSL 329
            ..|....|.|...|....:......||:|.:.|.|:..|...:||.|.:...||.|.:||..|..
 Frog   331 YLLLISQPAYFEEVFGFPISKVGLLSAVPHMVMTIIVPVGGQLADFLRSRKILSTTTVRKIMNCG 395

  Fly   330 AFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGILNTAVT 394
            .|.:....|:.:|:  ...|.::|:.:.::||.:..|..|.::|.:|::|.:|||||||.|...|
 Frog   396 GFGMEATLLLVVGY--SHTKAISISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGT 458

  Fly   395 VVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPW 446
            :..:|.|||||.:. ::..|.|||.||:|||::.:.|...|..|.:...|.|
 Frog   459 LSGMVCPLIVGAMT-KNKTREEWQNVFLIAAIVHYSGVIFYGIFASGEKQEW 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	136/429 (32%)
slc17a8	XP_002936892.1	MFS_SLC17A6_7_8_VGluT	79..502	CDD:340940	136/429 (32%)