Protein Alignment CG12490 and slc17a6b

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001122293.1
• Gene: slc17a6b / 100149756
• ZFINID: ZDB-GENE-030616-554
• Length: 584
• Species: Danio rerio
• Alignment Length: 473
• Identity: 150/473 - (31%)
• Similarity: 229/473 - (48%)
• Gaps: 32/473 - (6%)

  Fly     3 AETN--KGPV-------LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPN------- 51
            |:.|  |.|:       |..|::.|::..|.....|..|.|:||::|:|.|..|.:.|
Zfish    49 AQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKE 113

  Fly    52 FPEYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGW 116
            ..:::|.......|..|||||||:||..|||:..|.....|....:.::...:...| ....|.:
Zfish   114 KAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIP-SAARGHY 177

  Fly   117 QAYCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIG 181
            .....:|::.||.:|:.:|..|...:||:||.||:||...|..|...|.|.||.|:|::.:.. |
Zfish   178 GCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-G 241

  Fly   182 WPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHN------EDYHKTVIPVP 240
            |..:.||.......|...|.:.:.::..|...||.||..|||.|:..:      .|..||    |
Zfish   242 WSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKT----P 302

  Fly   241 WMAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYL 305
            |...:||.|..|:.:...|.:|....|....|.|...|...::......||||.|.|.|:..:..
Zfish   303 WRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGG 367

  Fly   306 IIADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGS 370
            .:||.|.:.|.||.|.:||..|...|.:....|:.:|:  ...|.:||:.:.::||.:..|..|.
Zfish   368 QLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGY--SHSKGVAISFLVLAVGFSGFAISGF 430

  Fly   371 SLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVY 435
            ::|.:|::|.:|||||||.|...|:..:|.|||||.:. :...|.|||.||:||:::.:.|...|
Zfish   431 NVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMT-KHKTREEWQYVFLIASLVHYGGVIFY 494

  Fly   436 LYFGTAVSQPWDAEDYLT 453
            ..|.:...||| |:..||
Zfish   495 GIFASGEKQPW-ADPELT 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	137/433 (32%)
slc17a6b	NP_001122293.1	MFS_SLC17A6_7_8_VGluT	73..498	CDD:340940	137/433 (32%)