DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30265 and TNA1

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_011776.1	Gene:	TNA1 / 853175	SGDID:	S000003492	Length:	534	Species:	Saccharomyces cerevisiae

Alignment Length:	510	Identity:	105/510 - (20%)
Similarity:	185/510 - (36%)	Gaps:	134/510 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PLLGMRHVQTLLLFFNITCLYIGRLNVGVAVVAMTNAESTNPDFPEYDWTLTQKSYILSSFFWGY 73
            ||:||       |:|   ...:.:.|:|.|.||..:        .:.....||.:..::.||..|
Yeast    94 PLMGM-------LYF---LSNLDKSNIGNAEVAGLS--------KDIHLVGTQYNTCVTVFFATY 140

  Fly    74 IITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCG---IRVLMGFAQGLIFP 135
            ::...:|..|.|..|...:|   |.....|.|::   :|....:.|..   :|:|:|..:|:|:|
Yeast   141 VLFDPIGTNLLKIMGPPLMM---SICLTCFGAIS---LGTAWVKNYAQLIVVRLLLGAFEGMIYP 199

  Fly   136 CIHQHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIA-------KSAIGWPGISYVSAGLA 193
            .|:.:|:    ...|....||....:......:..|.|:||       .|...|..|..|...::
Yeast   200 AINMYLS----VCYRREQYALRFAFVFSAACLSSSFGGLIAYGCSKISGSLKDWQYIYIVEGCIS 260

  Fly   194 LAWCAFWFVFAADNAEESRYITQEELHYIESSLK------HNEDYHKTVIPVPWMAIWTSAPFFA 252
            |.:..|:....:.|.|:|.:..:||..||....|      .:|.:.       |..:|
Yeast   261 LGFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEKFE-------WFQVW------- 311

  Fly   253 LMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRL 317
             ...:..:||..:.          .:..:|:.:   |....||.:.|.|..:..:...|:.....
Yeast   312 -QAVKDVKTWASAV----------ALFGIDLTT---FGLTVFLPIIITSMGFTNVRAQLMTVPIY 362

  Fly   318 SLTALRKIFNSLAFW-----IPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDL 377
            .|||:  :|...|.|     :....::|             |.:|.|:|:  ...:||.::.:..
Yeast   363 FLTAI--VFFICAVWSDRIKLRSPFILG-------------ACLTTSIGI--AIVLGSQVHGVRY 410

  Fly   378 SPNHASILMGI-VNTAANVVPI----------VTPLAVGL-------------IVHEDKNREEWQ 418
            ...:. :.||| ||.|.|.:.:          .|.|.:.|             .|.:||.|....
Yeast   411 FGVYI-LCMGIYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKG 474

  Fly   419 IVFIIAAVIFFIGNCV---FLYYG------------TAVSQPWDAEDYLTEKVPD 458
            :...:|..:|.|...|   |||..            ..:.:|...::.|::|.|:
Yeast   475 LSISLAFQVFSIFMTVVQIFLYKRENDKKKAIIDRCNELGEPIPYDERLSDKNPE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	98/495 (20%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	96/467 (21%)
TNA1	NP_011776.1	MFS_FEN2_like	87..490	CDD:340885	97/469 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I1824
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050