DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and slc17a5

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001070195.1	Gene:	slc17a5 / 767760	ZFINID:	ZDB-GENE-060929-1158	Length:	488	Species:	Danio rerio

Alignment Length:	469	Identity:	157/469 - (33%)
Similarity:	237/469 - (50%)	Gaps:	35/469 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TAEINKGPLLG-MRHVQTLLLFFNITCLYIGRLNVGVAVVAM------TNAEST-----NPDFPE 54
            |.:|.|.|..| .|:....|..:.....|..|:|:.||:|.|      .|..|:     |...|:
Zfish    23 TEDIQKAPACGSSRYGLAFLSCYGFFVAYALRVNLSVAMVDMLKNSSKANTSSSICPPHNIPVPK 87

  Fly    55 -------YDWTLTQKSYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIG 112
                   |||....:.:||.|||:||||||..||||.::||.|.::..|...:.||:.||||...
Zfish    88 HNHTAMVYDWNSETQGWILGSFFYGYIITQIPGGYLARKYGAKWLLGLGILCTVIFTLLTPLAAD 152

  Fly   113 FGEWQAY-CGIRVLMGFAQGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIA 176
            .|  ..| ..:|||.|..:|:.:|.:|...|.|:||.||:||..:|:||.:.|.|.|:..||.|.
Zfish   153 LG--AGYLIAVRVLEGIGEGVTYPAMHAMWASWAPPLERSRLLTISYTGAQLGTVVALPLSGQIC 215

  Fly   177 KSAIGWPGISYVSAGLALAWCAFWFVFAADNAEESRYITQEELHYIESSLKH----NEDYHKTVI 237
             ..:.|..:.|:...:.|.|...|..|.:::....:.||:.|..||.||||:    .:||
Zfish   216 -FYLDWTYVFYIFGAVGLLWFFLWICFVSNSPSSHKRITEAEKTYIMSSLKNELSPTQDY----- 274

  Fly   238 PVPWMAIWTSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSY 302
             :||.:|:.|.|.:|::||.....|...||...:|||||.||...::.|...||||:|..|:::.
Zfish   275 -IPWTSIFKSMPLWAIVVAHFSYNWTFYTLLTLLPTYMNDVLGFSIQQNGMLSALPYLGCWLLAL 338

  Fly   303 VYLIIADVLLAGNRLSLTALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGAT 367
            :...:||:|..........:||.|..:....|...|:..|:..... .||:|.:|||..:...:.
Zfish   339 LGGQLADLLRERFLFRTVIVRKAFTVVGMAGPAVFLVAAGYTGCNY-ILAVAFLTISSSLGGISA 402

  Fly   368 IGSSLNTIDLSPNHASILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGN 432
            .|.::|.:|::|::|.||:||.|:.|.:..:|.|: :...:.:.....||||||.|:|.|...|.
Zfish   403 SGFNINHLDIAPSYAGILLGITNSFATIPGMVGPV-IARSLTKSNTIPEWQIVFYISAAINIFGA 466

  Fly   433 CVFLYYGTAVSQPW 446
            ..|..:|....|||
Zfish   467 VFFTIFGKGTVQPW 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	152/456 (33%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	147/442 (33%)
slc17a5	NP_001070195.1	2A0114euk	27..488	CDD:129972	155/465 (33%)
slc17a5	NP_001070195.1	MFS	92..472	CDD:119392	135/390 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840