DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and slc17a8

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001076304.1	Gene:	slc17a8 / 563467	ZFINID:	ZDB-GENE-060503-416	Length:	590	Species:	Danio rerio

Alignment Length:	449	Identity:	141/449 - (31%)
Similarity:	225/449 - (50%)	Gaps:	35/449 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CLYIG-RLNVGVAVVAMTNAEST--------NPDFPEYDWTLTQKSYILSSFFWGYIITQFLGGY 82
            |:..| |.|:|||:|.|.|..:.        .|  .:::|.......|..|||||||:||..||:
Zfish    87 CISFGIRCNLGVAIVEMVNNNTVYINGTAVMQP--AQFNWDPETVGLIHGSFFWGYIVTQIPGGF 149

  Fly    83 LCKRYGVKSVMLWGSFASGIF-SALTPLFIGFGEWQAY-C--GIRVLMGFAQGLIFPCIHQHLAR 143
            :..:.....|     |.:.|| :::..:||.......| |  .:|:|.|..:|:.:|..|...::
Zfish   150 ISNKLAANRV-----FGAAIFLTSVLNMFIPSAARVHYGCVMFVRILQGLVEGVTYPACHGMWSK 209

  Fly   144 WSPPAERNRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGISYVSAGLALAWCAFWFVFAADNA 208
            |:||.||:||...|..|...|.|.||..:|::.: .:|||.:.|:.....:.|..||.:.|.::.
Zfish   210 WAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQ-YVGWPSVFYIYGVFGIIWYIFWILLAYNSP 273

  Fly   209 EESRYITQEELHYIESS------LKHNEDYHKTVIPVPWMAIWTSAPFFALMVARCCETWGLSTL 267
            .....|::||.:|||:|      |..:.:..||    ||...:||.|.:|::||..|.:|....|
Zfish   274 AVHPTISEEERNYIETSIGEGANLMSSTEKFKT----PWREFFTSMPVYAIIVANFCRSWTFYLL 334

  Fly   268 QAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKIFNSLAFW 332
            ....|.|...|....:......||:|.:.|.|:..:...:||.|.:...||.|.:|||.|...|.
Zfish   335 LISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGGQLADFLRSRKILSTTTVRKIMNCGGFG 399

  Fly   333 IPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGIVNTAANVVP 397
            :....|:.:||  ...:.:||:.:.::||.:..|..|.::|.:|::|.:|||||||.|....:..
Zfish   400 MEATLLLVVGF--SHTRAVAISFLILAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSG 462

  Fly   398 IVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGTAVSQPW-DAEDYLTEK 455
            :|.||.||.:. :.|.|.|||.||:||:::.:.|...:..:.:...|.| |.|:...||
Zfish   463 MVCPLIVGALT-KHKTRLEWQHVFVIASMVHYTGVIFYAIFASGEKQDWADPENTSDEK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	138/442 (31%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	135/429 (31%)
slc17a8	NP_001076304.1	2A0114euk	75..514	CDD:129972	138/441 (31%)
		MFS	81..503	CDD:119392	135/430 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582528
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750