DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30265 and CG7091

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_650243.2	Gene:	CG7091 / 41590	FlyBaseID:	FBgn0038099	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	110/508 - (21%)
Similarity:	205/508 - (40%)	Gaps:	71/508 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLGMRHVQTLLLFFNITCLYIGRLN-VGVAVVAMT--------------------NAEST----- 48
            |:|...:...:..|..|||:....| :|:.::.|.                    |..||
  Fly    22 LVGSVRLTYAICAFLATCLHAAMRNMLGMIILKMVMPRPEDALVVPAGLSRLTEGNVTSTGRCGS 86

  Fly    49 -----NPDFPE-----YDWTLTQKSYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIF 103
                 ||...|     ..||..|:......:::||:::..|.|||..|...|.:.:    .|.||
  Fly    87 PRVVFNPQIQETQSGDLPWTRNQELTFPGVYYYGYVVSISLSGYLADRCSSKRLFI----VSLIF 147

  Fly   104 SALTPLFI---GFGEWQAYCGIRVLMGFAQGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGN 165
            .|:..:.:   ....::|.....|:.|...|...|.:::....|:.|.||..|.:.:::|:..|:
  Fly   148 EAVAYILLPAMAHSSFEAGVVDLVICGLLAGCGNPAMYKLFVTWAHPTERTALLSFAYSGLLMGS 212

  Fly   166 VCAMFFSGMIAKSAIGWPGISYVSAGLALAW---CAFWFVFAADNAEESRYITQEELHYIESSLK 227
            :.....:..:  |..||....||..|:.|::   |.|   ...|..|:...|:.||:.|:.....
  Fly   213 MLVYPVASYL--SNFGWELSFYVVGGVGLSFGIACCF---LVYDTVEQHPRISNEEVDYLRQGKS 272

  Fly   228 HNEDYHKTVIPVPWMAIWTSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSAL 292
            ......:.|:.:||.::..:.|.:|.::.....|:....:...:|.:|...::.|::...|.||.
  Fly   273 QLGQQRQPVVTIPWKSLLAAPPVYAFILTHMFHTYTFLVIVQLMPRFMREAMEFDLREVGFLSAA 337

  Fly   293 PFLAMWIMSYVYLIIADVLLAGNRL------SLTALRKIFNSLAFWIPCATLIGIGFL-DQEQKN 350
            |:|. .|.|.|..|     |.|:.:      ....:|::...:.. |...:|||:..| :.:.|.
  Fly   338 PYLG-GICSKVMCI-----LGGSYVERRVGPDQNCVRRMLYGICS-ILTTSLIGVIILANCDDKI 395

  Fly   351 LAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGIVNTAANVVPIVTPLAVGLIVHEDKNRE 415
            |.:.:....:........|.....:..:|:.|.:|.|:.|..|::...:.|..|..:||.. :::
  Fly   396 LVLVMFAFMMATTDMGFSGYWPTLLYFAPSFAGLLSGLANGMAHLSGFLAPHLVAALVHTG-SKD 459

  Fly   416 EWQIVFIIAAVIFFIGNCVFLYYGTAVSQPWDAEDYLTEKVPDLAIAPAIHEA 468
            ||.:|.:...|...:...||.:..:...||||....: ||    ..:|:..|:
  Fly   460 EWNVVLMTLIVFNTMAMLVFAFCSSTNLQPWDPRSRM-EK----TASPSAQES 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	104/484 (21%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	100/468 (21%)
CG7091	NP_650243.2	2A0114euk	77..498	CDD:129972	97/438 (22%)
CG7091	NP_650243.2	MFS	115..482	CDD:119392	84/383 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970