DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30265 and CG9254

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	139/463 - (30%)
Similarity:	234/463 - (50%)	Gaps:	25/463 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EINKGPLLGMRHVQTLLLFFNITCLYIGRLNVGVAVVAM----------TNA-----ESTNP--- 50
            :::|..:|..|.:..::.||.|...|..|:.:..|:..:          |.|     :.::|
  Fly    13 KLSKFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSST 77

  Fly    51 -DFPEYDWTLTQKSYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFG 114
             :..:|||:..::..||:||:.|||:|...||.|..::|.|..:..|.|.:.||:.|||:.|.:|
  Fly    78 FEGGDYDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIVYG 142

  Fly   115 EWQAYCGIRVLMGFAQGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIAKSA 179
            ...|...:|||||..:|..||.:...||.|.|..||..||||...|.:.|::.....||.:. |:
  Fly   143 GADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVL-SS 206

  Fly   180 IGWPGISYVSAGLALAWCAFWFVFAADNAEESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAI 244
            :.||.:.||.|.:||.|...:.:....:.....||..||..::...:...:   |.....|:.||
  Fly   207 MDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEVPPPD---KNKPKTPFFAI 268

  Fly   245 WTSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIAD 309
            .||.|.:||:.|:....||...:.:.:|.||:.||...:|||..:|:||::.|||||.:...:||
  Fly   269 LTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVAD 333

  Fly   310 VLLAGNRLSLTALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNT 374
            .::..|.:|.|..|||...:|.:.|...::...:... .:.:.:||.||::|:......|..|..
  Fly   334 QMIKRNCMSTTNTRKIMTGVAAFGPAVFMVAASYAGC-NRGMVVALFTITMGLMGTYYAGMKLTP 397

  Fly   375 IDLSPNHASILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYG 439
            :|:|||:|..||.|.|....:..:|:|..|| ::..:....||::||.:|..:..:...|:..:.
  Fly   398 LDMSPNYAGTLMAITNGIGAITGVVSPYLVG-VMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWA 461

  Fly   440 TAVSQPWD 447
            :...||::
  Fly   462 SGDVQPFN 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	137/453 (30%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	134/438 (31%)
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	134/443 (30%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	125/384 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451934
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.890