DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and MFS17

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001015096.2	Gene:	MFS17 / 3354861	FlyBaseID:	FBgn0058263	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	135/457 - (29%)
Similarity:	228/457 - (49%)	Gaps:	45/457 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LLLFF----NITCLYIGRLNVGVAVVAM------TNAES---------TNPDFPEYDWTLTQKSY 64
            |:|:|    .....::.|.::..|:|||      |..:|         |..|    |.....||.
  Fly    37 LVLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQNQSLIKSQQILGTGTD----DQKTIVKSV 97

  Fly    65 ILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCGIRVLMGFA 129
            ::|||:|.|:::|.:||...:.:|.|.|..|...|:.:.|.:.|..... .:.|...:|.:.|||
  Fly    98 VISSFYWCYVLSQVVGGVATELFGTKCVFGWSQLATALCSFMMPSAAQL-HYIAVIVLRSIQGFA 161

  Fly   130 QGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGISYVSAGLAL 194
            .||.:|.::..:..|.|..||:|..: |..|...|........|.|. |..|||.|.|.:..|.|
  Fly   162 SGLTWPAMYAIVGYWIPLTERSRFMS-SFQGFSIGIGLTYPLCGFIL-SEWGWPYIFYTTGTLGL 224

  Fly   195 AWCAFWFVFAADNAEESRYITQEELHYIESSLKHNEDYHKTV-IPVPWMAIWTSAPFFALMVARC 258
            .||..|::.|.:...|...||::||:|||.::|  ::.:.:| :.|||:.|:.|.|.:|:.:.
  Fly   225 GWCILWYLLAFNTPREHPRITKDELNYIELNVK--KEVNSSVKVKVPWLQIFKSIPAWAIAIT-- 285

  Fly   259 CETWGLSTLQ----AQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSL 319
              |:|...:.    ...||:|..||..:.::|.|.|.:||:..:|.|.::..|||.::....|.|
  Fly   286 --TFGRIFVHYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSVLFCYIADKIVFYKVLCL 348

  Fly   320 TALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMT--ISVGVNSGATIGSSLNTIDLSPN-- 380
            |.:||:|.:|:..||...:..||::|    |:.|.|..  |:|...:.:..|:..|.|||:||
  Fly   349 TNVRKVFTALSQIIPGVLIYCIGYID----NVYILLTVWFIAVIFITASYAGAMANIIDLAPNYG 409

  Fly   381 HASILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGTAVSQP 445
            |::.::....|.......::||..|.||.::.:.::|:.||.::|:|..:....:..:|||..|.
  Fly   410 HSAAVLAFCQTIHMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISILTYLFYQLFGTAEIQT 474

  Fly   446 WD 447
            |:
  Fly   475 WN 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	135/457 (30%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	130/446 (29%)
MFS17	NP_001015096.2	2A0114euk	34..477	CDD:129972	135/457 (30%)
MFS17	NP_001015096.2	MFS	41..467	CDD:119392	128/442 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970