DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and MFS3

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	152/517 - (29%)
Similarity:	243/517 - (47%)	Gaps:	73/517 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTAEI-NKGPLLG----MRHVQTLLLFFNITCLYIGRLNVGVAVVAMTN---------------- 44
            ||.|: .||.:||    .|:|..||....:..:|..::|:.||:|||.|
  Fly     1 MTDEVPAKGSILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGH 65

  Fly    45 -------------AESTNP------------DFPEYDWTLTQKSYILSSFFWGYIITQFLGGYLC 84
                         .|..||            |.| :||:...:..:||.:||||:::|....::.
  Fly    66 GSVILSNASQVSLVEECNPPGGASNVTAKVEDGP-FDWSEPLQGTLLSCYFWGYLVSQIPLAHVA 129

  Fly    85 KRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCGI---RVLMGFAQGLIFPCIHQHLARWSP 146
            :.:..|.|||:....:.:.:.|||:|...    .|.|:   |||.|...|..||.:|..:|.|:|
  Fly   130 ENFSAKWVMLFSVAINVVCTLLTPVFTEL----HYGGLILMRVLEGVGGGASFPAMHVMIASWAP 190

  Fly   147 PAERNRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGISYVSAGLALAWCAFWFVFAADNAEES 211
            |.||..:..:.:.|...|...::..:| :..:..||..:.||...|:..|...|.:...||..:.
  Fly   191 PTERMVMSTIIYVGTSAGTALSILLAG-VCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQ 254

  Fly   212 RYITQEELHYIESSL--KHNEDYHKTVIPVPWMAIWTSAPFFALMVARCCETWGLSTLQAQIPTY 274
            |:|:.||...|.|||  :...::|..   |||..::||.||:|:::|..|..:|......:||.|
  Fly   255 RFISLEERQMITSSLGTEQKTEHHPA---VPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFY 316

  Fly   275 MNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKIFNSLAFWIPCATLI 339
            |..||..::.|||..||||:..|.|.|.....:.|.|.|..:::.|..||...|:...||...|:
  Fly   317 MKQVLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLL 381

  Fly   340 GIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGIVNTAANVVPIVTPLAV 404
            .:.::...... |:::|::.:........|...|.||::||.|..|:.:.||||.:..||.||.|
  Fly   382 VLCYIGCRHYE-AVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFV 445

  Fly   405 GLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGTAVSQPW---------DAEDYLTEKVP 457
            |.:...::|...|:|:|.:..|:|.:...||::.|:...|||         :|:|   ||.|
  Fly   446 GFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPKDPEAKD---EKTP 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	141/490 (29%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	134/465 (29%)
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	140/479 (29%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	119/387 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D46132at33392
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970