DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	476	Identity:	90/476 - (18%)
Similarity:	177/476 - (37%)	Gaps:	114/476 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TLLLFFNITCLYIGRLNVGVAVVAMTNAESTNPDFPEYDWTL--TQKSYILSSFFWGYIITQFLG 80
            |:::.:.:.  ::.|.|:|.|.||         ..|| |..|  .|.:.|.|.|:..:|:.:...
pombe    62 TIMILYLVA--FLDRSNIGNAKVA---------GLPE-DLKLKGDQFNIIASVFYVTFILFEMPT 114

  Fly    81 GYLCKRYGVKSVMLWGSFASGIFSALTPLFIGF-GEWQAYCGIRVLMGFAQGLIFPCIHQHLARW 144
            ..|.|:...|.::.:    ..|..:||.:|.|| ..:......|:::||.:..:|||:..:|
pombe   115 TLLMKKVQPKRMLAF----IVISYSLTTIFTGFCHNFGGLLAARLVLGFCEAGLFPCLALYL--- 172

  Fly   145 SPPAERNRLGALSHTGIECG-NVCAMF--------FSGMIAKSAIGWPGIS--------YVSAGL 192
                      .:.::.:|.. .:..:|        |.|:.|.:.:...|:.        ::..||
pombe   173 ----------TMIYSRVELAPRIAYLFASSALSGAFGGLFAYAVLHMDGVGGFAGWRWLFIIEGL 227

  Fly   193 ALAWC--AFWFVFAADNAEESRYITQEELHYIESSLKHNEDYHKTVIP---------VPWMAIWT 246
            ....|  |.:|:...|       ||:...    .|..|.|...|..:.         ..|..:.:
pombe   228 IGFVCGVAVYFIIPND-------ITKAWF----LSKTHQEMMRKRQLERAADLEAAHFDWKGVKS 281

  Fly   247 SAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVL 311
            :...|.:.:....| :|..|......|::..::     |...:::|....|.|.  ||::.|...
pombe   282 AFTDFKVYLYALSE-FGQDTCLYGFSTFLPAII-----SGMGYTSLSVQYMTIP--VYILGAATY 338

  Fly   312 LAGNRLS--------LTALRKIFNSLAFWIPCATLIGIGFLDQEQKN-LAIALMTISVGVNSGAT 367
            :|.:.||        :..:..||..:.:.:..|.        |..|: |..|....||||.:||.
pombe   339 IAASFLSDRFHHRGIILIIGNIFPIVGYILLLAC--------QNNKSVLYFACYLCSVGVYTGAG 395

  Fly   368 IGSSLNTIDLSPNH-----ASILMGIVNT----AANVVPIVTPLAVGLIVHEDKNREEWQIVFII 423
            :..:..:.:::|::     .|:.:.|.|:    |..:.........|.:.         .::.|.
pombe   396 LNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYRYPPKYIAGHLT---------SLIAIF 451

  Fly   424 AAVIFFIGNCVFLYYGTAVSQ 444
            .:.:..:.|..||.:..:..|
pombe   452 ISTVLHVVNIFFLKHQNSKKQ 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	90/476 (19%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	89/468 (19%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	85/456 (19%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	83/425 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050