DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	462	Identity:	104/462 - (22%)
Similarity:	193/462 - (41%)	Gaps:	78/462 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EINKGPLLGMRHVQTLLLFFNITCLYIGRLNVGVAVVA-MTNAESTNPDFPEYDWTLTQKSYILS 67
            ::.|..||.|..|.:.::.|.....::.|.|:|.|.|| ||.|.|...:         :.:..:|
pombe    48 KVEKKLLLKMDLVISPIIGFLYLMAFLDRSNIGNAAVAGMTEALSLYGE---------RLNVAVS 103

  Fly    68 SFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCGI---RVLMGFA 129
            .|:..||:.:.....|.||.....::.:.|||    .::|.||.||  ..:|.|:   |:::|..
pombe   104 IFYVLYILVETPSVVLVKRIKASRMLAFISFA----WSMTVLFSGF--MSSYGGLIATRLILGLL 162

  Fly   130 QGLIFPCIHQHL-ARWSPPAERNRLGAL-SHTGI--ECGNVCAMFFSGMIAKSAIGWPGISYVSA 190
            :|.:||.::.:| ..::...:..||..| :..|:  ..|.:.|.....:.|.:..||..| |:..
pombe   163 EGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWI-YIVE 226

  Fly   191 GL----ALAWCAFWFVFAADNAEESRYITQEELHYIESSLKHNEDYH----------KTVIPVPW 241
            ||    .:..|.|   ...|..|.:.::|:||..........|..||          :.....|.
pombe   227 GLVSFIGVPLCLF---ALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVRKAFKDPK 288

  Fly   242 MAIWTSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLI 306
            :.:..::.|.|.||     .:|.|:.   :|..:.|:..:.:::|  :..:|.....::|:::
pombe   289 VYVSATSQFCADMV-----LYGFSSF---LPVIIKGLGFVGLQTN--YMTIPVYIAGVISFLF-- 341

  Fly   307 IADVLLAGNRLSLTALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSS 371
               |....:|..|.|:        :.|..:|::.:|::.....:...|..|.:..:..|..||..
pombe   342 ---VAWLSDRTQLRAV--------YLISASTVVAVGYIIMLASDSNAAKYTATYIIAIGCYIGPG 395

  Fly   372 LNTIDLSPNHA-----SILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQI--VFIIAAVIFF 429
            ||...|:.|.|     :..:||..|.||...||...     ::..||..::.:  .|.:..||
pombe   396 LNLGWLNNNVAGHYKRATAIGIQQTLANSSGIVAGQ-----IYRSKNAPKYILGNAFTLGCVI-- 453

  Fly   430 IGNCVFL 436
            :|...::
pombe   454 VGGLAYV 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	100/452 (22%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	99/448 (22%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	98/442 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050