DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and liz1

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001342731.1	Gene:	liz1 / 2540342	PomBaseID:	SPBC2G2.01c	Length:	514	Species:	Schizosaccharomyces pombe

Alignment Length:	461	Identity:	89/461 - (19%)
Similarity:	151/461 - (32%)	Gaps:	120/461 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PLLGMRHVQTLLL------FFNITCL-----YIGRLNVGVAVVAMTNAESTNPDFPEYDWTLTQK 62
            |..|:..|:..||      ..:..|:     |:.|.::..|.::     ....|...:...|...
pombe    13 PYYGLNKVEQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLS-----GMQEDLKMHGNELQDI 72

  Fly    63 SYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCGIRVLMG 127
            :.:   |..||||.|..|.|..:|...:   ||.|..:.::..:|.........:|...:|..|.
pombe    73 NVV---FTCGYIIGQLPGSYALQRVPAR---LWFSVMNILWGLMTIFSFAVHSVRALMILRFFMA 131

  Fly   128 FAQGLIFPCIHQHLARWSPPAER-NRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGIS----- 186
            .|:...|...|..|..|...:|. .|.|..|.:|: .|.:.|.:....:..|..|..|:|
pombe   132 VAEASTFAGTHYILGAWYKESELCKRAGIFSASGL-VGTMFAGYLQTAVHSSLNGKGGLSGWRWL 195

  Fly   187 YVSAGLALAWCAFWFVFAADNAEESR---YITQEELHYIESSLKHNEDYHKTVIPVPWMAIWTSA 248
            ::..|:.....:.:.:|...:..|:.   |.|::|.   |.|.|......|.. |:...||..
pombe   196 FIIDGILTIPLSLYGLFLFPDVPETTKAPYFTEQEK---ELSFKRLPARPKKK-PLTLKAIKD-- 254

  Fly   249 PFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLA 313
                  :.|....:||..|                              ||.|.....||..:|.
pombe   255 ------IVRSWRIYGLCIL------------------------------WIFSGETQAIAVNVLM 283

  Fly   314 GNRLSLTALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLS 378
            |.                |:..:....:.     |.|....::| :|||.|  |:|:|:.:..|:
pombe   284 GQ----------------WMKWSNKFSVA-----QINNYPTVIT-AVGVVS--TLGASVISDKLA 324

  Fly   379 PNHA---SILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGT 440
            .|..   .:.:.::.|.:..:.:.                 |.:........:|...|.  |.|.
pombe   325 GNPRWPFGLFLCVITTVSATILLA-----------------WNVPDGAKFFAYFASGCT--YAGQ 370

  Fly   441 AVSQPW 446
            ||...|
pombe   371 AVWFSW 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	87/456 (19%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	81/442 (18%)
liz1	NP_001342731.1	MFS_1	37..401	CDD:311564	84/437 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050