DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and SPCC417.10

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_588287.1	Gene:	SPCC417.10 / 2539419	PomBaseID:	SPCC417.10	Length:	508	Species:	Schizosaccharomyces pombe

Alignment Length:	500	Identity:	103/500 - (20%)
Similarity:	178/500 - (35%)	Gaps:	155/500 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 FNITCL-----YIGRLNVGVAVVAMTNAESTNPDFPEYDWTLTQKSYILSSFFWGYIITQFLGGY 82
            |.:.||     ::.:.:...||: |...|....:...|.|:.|       :|:.||::.:|....
pombe    66 FPVMCLVYCIQFLDKTSNSYAVI-MGLKEDLKMEGQMYSWSGT-------AFYLGYLVFEFPASL 122

  Fly    83 LCKRYGVKS-----VMLWGSFASGIFSALTPLFIGFGEWQAYCGIRVLMGFAQGLIFPCIHQHLA 142
            |.:|:.:..     :::||........|..|.||         .:|||:|..:....|......|
pombe   123 LLQRFPLSKTLCVFLVIWGFLLCMTSVANYPGFI---------ALRVLLGMMESAASPGFILLTA 178

  Fly   143 RWSPPAER----------NRLGALSHTGIECGNVCAMFFSGMIAKSAI---GWPGISYVSAGLAL 194
            :|...:|:          |.||.:..:       |..:  |:..::::   ||..|..:...||:
pombe   179 QWYKRSEQQLRTSVWVAFNGLGQILGS-------CMAY--GLAKRTSLPMRGWKLIFIICGVLAI 234

  Fly   195 AWCAFWFVFAA---DNAEESRYITQEELHYIESSLKHNE-----------DYHKTVIPVPWMAIW 245
               ...||..|   ||..::.::|:|:...:...|:.|:           .:.:|::.:
pombe   235 ---FLGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKLYQFKETMLDI------ 290

  Fly   246 TSAPFFALMVARCCETW--GLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIA 308
                          .||  .:|::...||   ||.:       ..||:|  |....|.|
pombe   291 --------------RTWIMFVSSVLLNIP---NGGI-------GTFSSL--LIKGTMGY------ 323

  Fly   309 DVLLAGNRLSLTALRKIFNSLAFWIPCAT-----LIGIGFLDQ-EQKNLAIALMTISVGVNSGAT 367
            |.|               .:|...:|...     ||..|||.. ..|.:.:|.:|..:     |.
pombe   324 DTL---------------QTLLMGLPAGACEFGGLIAFGFLSLFIHKRMVLATITTCI-----AL 368

  Fly   368 IGSSLNTIDLSPNH--ASILMGIVNTAANVV--PIVTPLAVGLIVHEDKNREEWQIVFIIAAVIF 428
            |||.|.:....|..  |...:.:|:..|.:|  .|::..|.|   :..|         :...||:
pombe   369 IGSCLLSFAGPPRAQLAGYYLLMVSPGAMIVMFAIISSNASG---YTKK---------VTVGVIY 421

  Fly   429 FIGNCVFLYYGTAVSQPWDAEDYLTEK-------VPDLAIAPAIH 466
            .||.||....|....:..||.:|:..|       ...|...||::
pombe   422 LIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATLVTFPALY 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	98/475 (21%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	95/463 (21%)
SPCC417.10	NP_588287.1	MFS	66..436	CDD:119392	96/468 (21%)
SPCC417.10	NP_588287.1	2A0114	71..468	CDD:273326	101/494 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	4	4.050