DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and cima-1

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001294208.1	Gene:	cima-1 / 24104589	WormBaseID:	WBGene00018473	Length:	543	Species:	Caenorhabditis elegans

Alignment Length:	492	Identity:	116/492 - (23%)
Similarity:	200/492 - (40%)	Gaps:	71/492 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LLLFFNITC----LYIGRLNVGVAVVAMTNAESTNPDFPEY------DWTLTQKSYILSSFFWGY 73
            |:|...:.|    |.|...|:.||::.||:.       |.:      :|...|:..:|::...|.
Worm    68 LMLAAMLCCCFITLSISSSNLAVALICMTSC-------PVHGYGGTLEWQSQQEGLVLAAQNAGS 125

  Fly    74 IITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCGIRVLMGFAQGLIFPCIH 138
            :| ..:.|....|...|.::..|.....|.:.:.||......|.|... |:.:|.:...:.|.::
Worm   126 LI-MIVTGMWADRLNGKWMVFIGLLLCCIGNLMLPLLASKSFWFAVLA-RISIGASDACLMPAVN 188

  Fly   139 QHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIA--KSAI-GWPGISYVSAGLALAWCAFW 200
            ..:.||.|.|||.....|...|.:.|.:..:..:|.:.  |..: |||.|.|:||.:::....||
Worm   189 SLITRWFPQAERPAAIGLISGGRQIGTLFILPTAGYLCTRKDILDGWPAIFYLSATISVLVTVFW 253

  Fly   201 FVFAADNAEESRYITQEELHYIES-----SLKHNEDYHKTVIPVPWMAIWTSAPFFALMVARCCE 260
            ..|.||...:...|:..|..:||:     |:....|..:.   ||:.|:..|.|.:|.:.|..|.
Worm   254 IPFGADKPAKQICISSREKEFIETRIACESIGKRTDRTRR---VPYGAMLHSKPLWACIFALICH 315

  Fly   261 TWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKI 325
            .:.|..:...:|.||..||:.....|...:|||.|.:::.......::..|....||..|.:.|.
Worm   316 EYPLVIMLQFLPNYMRDVLEFAPTKNGIIAALPILCLFLSKTFSSSLSSYLTTKLRLDKTFVCKG 380

  Fly   326 FNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNT-------IDLSPNHAS 383
            ||::|.......:..:.|.::|...||:..:       .||.|.:.|:|       :.::|..:.
Worm   381 FNAVASAGLAICISFVPFFNKESAFLAVFCL-------CGAMIFAGLHTPGVITAMVQIAPAFSG 438

  Fly   384 ILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGTAVSQPWDA 448
            |:.|....|.....|...:....|| :..:..||.:||.::|::..:...||..:|:|..:.|.|
Worm   439 IITGWSFFAVAWFSIGNKILTKYIV-QSGSVTEWGMVFRVSALVAALPVIVFTIWGSADREWWAA 502

  Fly   449 EDYLTEKVPDLAIAPAIHEAGKGIDGPSQKSMILKFH 485
                                      ||.|..:..||
Worm   503 --------------------------PSSKCSVASFH 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	111/455 (24%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	107/443 (24%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	113/483 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930