DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and Slc17a8

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_892004.1	Gene:	Slc17a8 / 216227	MGIID:	3039629	Length:	601	Species:	Mus musculus

Alignment Length:	443	Identity:	145/443 - (32%)
Similarity:	222/443 - (50%)	Gaps:	27/443 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CLYIG-RLNVGVAVVAMTNAESTNPD-FPE-----YDWTLTQKSYILSSFFWGYIITQFLGGYLC 84
            |:..| |.|:|||:|.|.|..:...| .||     ::|.......|..|||||||:||..||::.
Mouse   100 CISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFIS 164

  Fly    85 KRYGVKSVMLWGSFASGIFSALT-PLFIGFGEWQAY-C--GIRVLMGFAQGLIFPCIHQHLARWS 145
            .::....|     |.:.||...| .:||.......| |  |:|:|.|..:|:.:|..|...::|:
Mouse   165 NKFAASRV-----FGAAIFLTSTLNMFIPSAARVHYGCVMGVRILQGLVEGVTYPACHGMWSKWA 224

  Fly   146 PPAERNRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGISYVSAGLALAWCAFWFVFAADNAEE 210
            ||.||:||...|..|...|.|.||..:|::.: .|||..:.|:.....:.|..||.:.|.:....
Mouse   225 PPLERSRLATTSFCGSYAGAVVAMPLAGVLVQ-YIGWASVFYIYGMFGIIWYMFWLLQAYECPAA 288

  Fly   211 SRYITQEELHYIESSLKHNEDYHK-TVIPVPWMAIWTSAPFFALMVARCCETWGLSTLQAQIPTY 274
            ...|:..|..|||:|:....:... :....||...:||.|.:|::||..|.:|....|....|.|
Mouse   289 HPTISNAERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAY 353

  Fly   275 MNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKIFNSLAFWIPCATLI 339
            ...|....:......||:|.:.|.|:..:...:||.|.:...|:.||:|||.|...|.:....|:
Mouse   354 FEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLL 418

  Fly   340 GIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGIVNTAANVVPIVTPLAV 404
            .:||  ...|.:||:.:.::||.:..|..|.::|.:|::|.:|||||||.|....:..:|.||.|
Mouse   419 VVGF--SHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIV 481

  Fly   405 GLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGTAVS---QPWDAEDYLTE 454
            |.:. :.|.|||||.||:|||::.:.|   .::||...|   |.|...:.|:|
Mouse   482 GAMT-KHKTREEWQNVFLIAALVHYSG---VIFYGVFASGEKQDWADPENLSE 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	143/437 (33%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	138/422 (33%)
Slc17a8	NP_892004.1	2A0114euk	88..526	CDD:129972	143/437 (33%)
		MFS	93..515	CDD:119392	140/426 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	576..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11710
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820