DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	140/473 - (29%)
Similarity:	233/473 - (49%)	Gaps:	59/473 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CLYIG-RLNVGVAVVAMTNAEST-------------------------------NPDFPEYDWTL 59
            |:..| |.|:|||:|:|.|..:|                               :.:..:::|..
  Rat    74 CISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQTPYRSVHKQEAVTPTVGDIQGGDTEKAQFNWDP 138

  Fly    60 TQKSYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTP--LFIGFGEWQAYCGI 122
            .....|..|||||||:||..||::|:::....|..:...|:...:.|.|  ..:.:|     |.|
  Rat   139 ETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYG-----CVI 198

  Fly   123 --RVLMGFAQGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGI 185
              |:|.|..:|:.:|..|...::|:||.||:||...:..|...|.|.||..:|::.:.: ||..:
  Rat   199 FVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYS-GWSSV 262

  Fly   186 SYVSAGLALAWCAFWFVFAADNAEESRYITQEELHYIESSLKHNEDYHKTVIPV-----PWMAIW 245
            .||.....:.|..||.:.:.::......|::||..|||.::..:.   |.:.||     ||...:
  Rat   263 FYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESA---KLMNPVTKFNTPWRRFF 324

  Fly   246 TSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADV 310
            ||.|.:|::||..|.:|....|....|.|...|...::......||||.|.|.|:..:...|||.
  Rat   325 TSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADF 389

  Fly   311 LLAGNRLSLTALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTI 375
            |.:.:.:|.|.:||:.|...|.:....|:.:|:  ...|.:||:.:.::||.:..|..|.::|.:
  Rat   390 LRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGY--SHSKGVAISFLVLAVGFSGFAISGFNVNHL 452

  Fly   376 DLSPNHASILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGT 440
            |::|.:|||||||.|....:..:|.|:.||.:. :.|.|||||.||:||:::.:.|   .::||.
  Rat   453 DIAPRYASILMGISNGVGTLSGMVCPIIVGAMT-KHKTREEWQYVFLIASLVHYGG---VIFYGV 513

  Fly   441 AVS---QPWDAEDYLTEK 455
            ..|   |||...:.::|:
  Rat   514 FASGEKQPWAEPEEMSEE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	139/466 (30%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	133/451 (29%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	135/455 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342470
Domainoid	1	1.000	47	1.000	Domainoid score	I11657
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850