DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30265 and SLC17A4

DIOPT Version :9

Sequence 1:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_005486.1	Gene:	SLC17A4 / 10050	HGNCID:	10932	Length:	497	Species:	Homo sapiens

Alignment Length:	482	Identity:	123/482 - (25%)
Similarity:	226/482 - (46%)	Gaps:	44/482 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EINKGPLLGMRHVQTLLLFFNITCLYIGRLNVGVAVVAMT---------NAESTNP--------- 50
            |.::.....:||...|:|......:|..::|:.:|:.||.         ||.:..|
Human    26 ECSRKGFCSVRHGLALILQLCNFSIYTQQMNLSIAIPAMVNNTAPPSQPNASTERPSTDSQGYWN 90

  Fly    51 ----DF----PEYDWTLTQKSYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALT 107
                :|    |.|||:...:..||||..:|..:.....||:...:|.|.|:..|.|.|...:...
Human    91 ETLKEFKAMAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFI 155

  Fly   108 PLFIGFGEWQAYCGI------RVLMGFAQGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGNV 166
            ||       .|..|:      |::.|.||.::....:....:|:||.||::|..::.:|...|:.
Human   156 PL-------AANAGVALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSF 213

  Fly   167 CAMFFSGMIAKSAIGWPGISYVSAGLALAWCAFWFVFAADNAEESRYITQEELHYIESSLKHNED 231
            ..:...|::.:: ||||.:.|:..|:..|.|..||....|:.....:|:..|..||..||...:.
Human   214 IVLLAGGLLCQT-IGWPYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVCSLAQQDC 277

  Fly   232 YHKTVIPVPWMAIWTSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLA 296
            .....:|:  .|:..|.|.:|::|:..||.|...|:.|..|||::.||..:::.:...|||||:.
Human   278 SPGWSLPI--RAMIKSLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVV 340

  Fly   297 MWIMSYVYLIIADVLLAGNRLSLTALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVG 361
            ..|...:..::||.||:...|.|..:||:|.::....|...|:.:.:: :...::.:..:.:|..
Human   341 GCICIILGGLLADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWV-RSSHSMTMTFLVLSSA 404

  Fly   362 VNSGATIGSSLNTIDLSPNHASILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAV 426
            ::|....|:.:|.:|::|.:...|.|::...|::...::|.|.|..:.:| :...|:.||:::|.
Human   405 ISSFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAGFFISQD-SEFGWRNVFLLSAA 468

  Fly   427 IFFIGNCVFLYYGTAVSQPWDAEDYLT 453
            :...|...:|.:|.|..|.|..|...|
Human   469 VNISGLVFYLIFGRADVQDWAKEQTFT 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	120/467 (26%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	114/451 (25%)
SLC17A4	NP_005486.1	UhpC	30..491	CDD:332119	120/472 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148629
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740