Protein Alignment CG42284 and LOC1279236

DIOPT Version :10

• Sequence 1: NP_611720.3
• Gene: CG42284 / 37621
• FlyBaseID: FBgn0259179
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_061511315.1
• Gene: LOC1279236 / 1279236
• VectorBaseID: AGAMI1_014371
• Length: 1524
• Species: Anopheles gambiae
• Alignment Length: 749
• Identity: 224/749 - (29%)
• Similarity: 331/749 - (44%)
• Gaps: 214/749 - (28%)

  Fly    10 SENDNDDDDEDVIASDSKGAN--------PQEG---------------QQPGAGAQPPE--DD-- 47
            :..|:||||......||..|:        |.|.               .||.. ..||:  |:
Mosquito   725 NHGDDDDDDNSEANDDSNNADVKIASYRTPDENATSEQLLEKTAETHPDQPEL-EDPPQAVDETS 788

  Fly    48 ----------------------------GNESLTSAMAIEGFVHGAPEDYTVQSQT--AVDENER 82
                                        ..|:.:..:.|||.|.|.|:...:|||.  .|:.:::
Mosquito   789 SAKEEPMARTEIETVTQSATSTQLATAAATEASSQVLEIEGTVQGEPDQGQLQSQNDPPVEHDDQ 853

  Fly    83 ------IKRIVESGDLEQLAEIVLNGEGGSLVGLKSPEPEIQAFLNNVPSYMEKIHRVHDAARDG 141
                  ::..::|.||||||.|||||||..|:|.||.:.||||||:|||:||.||.|||.|||:|
Mosquito   854 PNLQQTVQDAIDSADLEQLAAIVLNGEGKQLIGRKSDQTEIQAFLDNVPAYMGKIRRVHLAAREG 918

  Fly   142 GLLALQQALDRRKFAIAKNDISPNGSTPLHVAVLFGHTDIVRYLASRFPETMTITDNDGRTPLHY 206
            .|..||.||||||||.||:::||:|:||||||.:|||..||||||.|||||::.||:||||||||
Mosquito   919 SLRDLQSALDRRKFATAKDEVSPHGATPLHVATIFGHAGIVRYLAGRFPETLSATDDDGRTPLHY 983

  Fly   207 AATIKDNGHFYNMLLQLGANPKSLDKLGHSAEFYLDKEKAKNILNYTELLNIFGA-EELENQLLN 270
            |||:||||||||:|..||||||..|.|.||||:||...:::.||::.:||..:|| |||.:::||
Mosquito   984 AATLKDNGHFYNLLTHLGANPKVEDSLNHSAEYYLGHVQSQGILSHRQLLRDYGAKEELADEMLN 1048

  Fly   271 DQGQAQPVSFQANPIFKTEQGKYLADSLADPLIKALTEIANKRPRDPVAYLTNYLQHFMGDRKPM 335
            ||                         :.|.|..|      :||.|.|..||...:.|....:|:
Mosquito  1049 DQ-------------------------VPDDLHSA------RRPLDDVDTLTTLERCFKIIHEPI 1082

  Fly   336 TEVQVHSGSSKASTSSTSTLALPKSNASSNQRLGNTRNGPGPTNADLIELDA-------RSVAED 393
            .::.:.|            :.||            |.:.||..::..|.:.:       |||.:
Mosquito  1083 DDLMIKS------------VGLP------------TNSVPGSASSLRILITSYLARFLKRSVFD- 1122

  Fly   394 EDAEGALAVQHMEERDEHGQ-SMLHFACARSHRRGAL------YTLIEESGIDITYRDELYRTAR 451
                   .|:..:.|.:|.. .::..|..::.:...|      ..:|.:..:.:.:::.|....:
Mosquito  1123 -------KVKKRQTRLDHNLFDLIWPAMKKATKEKRLDEDLNVGIVIPDYDVFVVFQEFLVPLIK 1180

  Fly   452 DV----SLQANQPNNAAE-IDRYVMAQAVIGDVEPFE----------QLALQGYDHILDIEDENG 501
            ||    ..|...|:.|.: ..||     .|.|.:|..          .:..:..|.:....|.:|
Mosquito  1181 DVHCMEGTQPLMPHPAMQFFPRY-----AINDQQPDAAASPTASNNGNILRENPDSVQLNLDTSG 1240

  Fly   502 QSITD-VVQSRQNAALGEFLANLKALEESREELHQMIRENNMERVVELTNVANAKWLIRTKNYYG 565
            :.||. |::..:|....||..||...:  .|::.::|    ..||:.: :..:|........||.
Mosquito  1241 KYITGCVIECARNLDAYEFPLNLGIAQ--LEQVERLI----TARVLSM-DFVHATGETELGTYYS 1298

  Fly   566 RTALHIAVLKESEEMVQHMVKICPEGLKITDNLERTVLHYAMGTNALESVSRILIQNGAKRTAKD 630
            ..    .:|:...|:                   ||:|    .||.|  :..:|......:||:.
Mosquito  1299 MN----EILENPSEI-------------------RTIL----ATNGL--LIPLLDHTDPYQTAES 1334

  Fly   631 --LKGRQPSY-------------YFINKADILRL 649
              :.||...|             .::|..|.|||
Mosquito  1335 IAINGRYWPYGRGVYVSVDGSLVVWVNAQDHLRL 1368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42284	NP_611720.3	Ank_2	135..231	CDD:463710	69/95 (73%)
		ANK repeat	165..197	CDD:293786	21/31 (68%)
		Dpy-30	289..330	CDD:428357	10/40 (25%)
		Ank_2	533..630	CDD:463710	17/96 (18%)
		ANK repeat	564..596	CDD:293786	3/31 (10%)
		ANK repeat	598..630	CDD:293786	9/31 (29%)
LOC1279236	XP_061511315.1	None