Protein Alignment stl and Adamtsl2

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_084257.1
• Gene: Adamtsl2 / 77794
• MGIID: 1925044
• Length: 957
• Species: Mus musculus
• Alignment Length: 608
• Identity: 127/608 - (20%)
• Similarity: 187/608 - (30%)
• Gaps: 204/608 - (33%)

  Fly   663 PPLLHDYNPMDNELPGSPSN----WGEWSEPSACESGCLYG---------QSRRLLEGSTGLRTL 714
            |....|.:|..|.|.|....    ||||::.:||...|..|         |.||.....||.||
Mouse    26 PTEASDNSPTSNSLEGGADTTAYWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGTGNRT- 89

  Fly   715 NRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCM---------QARKSDPELTGEG 770
                      |:|..:|:..|...:|   |... ..|..:.|:         :|.:..|....:.
Mouse    90 ----------CVGTSKRYQLCRVQEC---PPDG-RSFREEQCVSFNSRVYDGRAYQWKPLYPDDY 140

  Fly   771 QQLPSTLDASCKIFCRTRTNGTKSRRWTFP--DGTTCKAKQHNPEDIT-YCISGRCERFSCDNST 832
            ..:.|   ..|.:.|.| .:|  .|:.|.|  |||:||.     .|:. .|:||:||...||...
Mouse   141 VHISS---KPCDLHCST-VDG--QRQLTVPARDGTSCKL-----TDLRGVCVSGKCEPIGCDGVL 194

  Fly   833 SNFFKMDS-SFCEARSVRPTRDSSDQESRQQTNRQRYA---------------ERQEG------- 874
            .:...:|. ..|:......|..:.:.  |:..|...|:               ||::.
Mouse   195 FSTHTLDKCGVCQGDGSSCTHVTGNY--RKGNNHLGYSLVTHIPAGARDIQIVERKKSADVLALA 257

  Fly   875 ---------------KPQKNHYENEVAK--RP--------SY-------GQGNHI-------NAP 900
                           .|:..:....|.|  ||        .|       .||.::       .:|
Mouse   258 DEAGFYFFNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSP 322

  Fly   901 ASPYKRRNYHKPYPPEIPRPPPPASASLIALDRSSSSESEWVAHPGCHSNCMTDSKGVQGVTS-- 963
            :..::......|:...:  ||...|.|..|...:.|:|.:.:           ||..:.|...
Mouse   323 SITFEYTLLQSPHMHHL--PPVYYSFSEAASQSTESTERQEL-----------DSARLLGFMQHN 374

  Fly   964 ----RLTGVESIQLCSYRIQP----CERLQTAAEYAEQTCARYRQKV-------RGLSGHGAQIS 1013
                |.|..|.:.|.|...||    .|...:..:.:.:.|.:....|       :|...|.|...
Mouse   375 GSLYRQTSSERLGLNSQLFQPPAPEVELGPSRGQESNEVCKQASGGVCEGPPRGKGFQDHNATGR 439

  Fly  1014 A-SIDEPDRSCR--------------------VGCQDEFIKYRYYLVNGRNGHFPPGT-RCSPVG 1056
            | |.|:.||...                    .|.:.|    .:.|....|..|..|. |.||..
Mouse   440 AFSADKDDREISAHFTSHELLSANTISDQLLGTGSESE----EFSLNETMNSIFAQGAPRSSPAE 500

  Fly  1057 KRYCVY------------GRCLEFGDD------DLPLDKTHISLGQL--------RTR---RKRS 1092
            ..|..|            |..||...|      :.|...|..|...|        |||   ||:.
Mouse   501 SLYVDYEENEGPAAYLINGSYLELSSDRINTSSEAPFPNTSASPPNLAGNRTHKARTRPKARKQG 565

  Fly  1093 SISNDLFNITEIFIKPSHSDISA 1115
            ....|::.    :...||...||
Mouse   566 VSPADMYR----WKLSSHEPCSA 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801
		ADAMTS_CR_2	561..625	CDD:465496
		TSP1	683..741	CDD:214559	19/66 (29%)
Adamtsl2	NP_084257.1	TSP1	50..106	CDD:214559	20/69 (29%)
		ADAMTS_CR_3	<167..213	CDD:437068	15/50 (30%)
		ADAMTS_spacer1	216..330	CDD:461796	14/115 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..568		9/35 (26%)
		TSP1_ADAMTS	632..691	CDD:465950
		TSP1_ADAMTS	695..743	CDD:465950
		TSP1_ADAMTS	747..800	CDD:465950
		TSP1_ADAMTS	804..860	CDD:465950
		TSP1_ADAMTS	863..913	CDD:465950
		PLAC	922..953	CDD:462560