Protein Alignment stl and Adamts4

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_076449.1
• Gene: Adamts4 / 66015
• RGDID: 621242
• Length: 851
• Species: Rattus norvegicus
• Alignment Length: 1025
• Identity: 234/1025 - (22%)
• Similarity: 346/1025 - (33%)
• Gaps: 336/1025 - (32%)

  Fly    29 SSSSSSTSSTNPKS--VNIELRR------KRSLHYNGIELDKNTLVGHLREHERALIFGSRSPEE 85
            |:.:.|....:|:.  ....|||      .|::.::|:|           ..::.|:..|..|
  Rat     9 STGTMSRMGLHPRRGLTGHRLRRLQPCLPPRTVPFSGLE-----------RWQQLLLLASLLP-- 60

  Fly    86 APEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPSEDGNGPLPPEEEEQEAGE 150
                 |...|...|.|::.:...|..|.:...|.....|...| ||:   .|.:...|.||:.|.
  Rat    61 -----LAWSASPLPREEEIVFPEKLNGSSIIPGSGVPARLLYR-LPA---FGEILLLELEQDPGV 116

  Fly   151 DVEARLQLQ---QSPQLIDDAFIFIRRTENGTQF---VEHSPQLLKRLERCFYRSPAAALDLCEP 209
            .||. |.:|   |:|:::..|       |.||..   :...|:.:..|.             .:.
  Rat   117 QVEG-LTVQYLGQAPEMLGGA-------EPGTYLTGTINGDPESVASLH-------------WDR 160

  Fly   210 GNVRGVFQQNGSDLVIHPLP-----ARFGTGTHVLYQARVDKSGGGYSEASSRRTASPLDSQLQF 269
            |.:.||.|..|::|.:.||.     :..|.|.|:|                  |..||..::
  Rat   161 GALLGVLQYRGAELHLQPLEGGALNSAGGPGAHIL------------------RRKSPASNR--- 204

  Fly   270 EPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIE 334
                    .|...::|.|...||:               .:|.:|:   |..||        |:|
  Rat   205 --------GPICNVKAPSGSPSPI---------------SRRNKRF---ASLSR--------FVE 235

  Fly   335 TAIFVDSDLYA-HMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDP 398
            |.:..|..:.| |         .:.:..:||.::......:.||::...:|.|:.||.|..|...
  Rat   236 TLVVADDKMAAFH---------GAGLKHYLLTVMAAAAKAFKHPSIRNPVNLVVTRLVILGSGQE 291

  Fly   399 PGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKG 463
            ...|.....:. |.|||.||:.|||.:|:||.|:|.|::.|..||.    |.:....:|||.|..
  Rat   292 VPQVGPSAAQT-LRSFCTWQKGLNPPNDSDPDHFDTAILFTRQDLC----GVSTCDALGMAGVGT 351

  Fly   464 MCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISC-------DPTMHIMSPKLG--SGK 519
            :|....||.|.|....:|.|..|||:||...|.||..: .|       ..:.|:|:|.:.  ..:
  Rat   352 VCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSK-PCANLNGQGSSSRHVMAPVMAHVDPE 415

  Fly   520 VTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQAST 584
            ..||.||..::.|||.:....||.|:.........|    .||:.::|::||.|.||.:
  Rat   416 EPWSPCSARFITDFLDNGYGHCLLDKPEAPLHLPVT----FPGKDYDADRQCQLTFGPD------ 470

  Fly   585 QSKMEICRDLHCRQDGLP------W------------TSH-PALEGTECGPNMWCRGGTCEARSS 630
                    ..||.|  ||      |            |.| |..:||.|||...|.||.|
  Rat   471 --------SSHCPQ--LPPPCAALWCFGHLNGHAMCQTKHSPWADGTPCGPAQACMGGRC----- 520

  Fly   631 KQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESG 695
                         .|:.:                 |.|:|     :| ....||.|.....|...
  Rat   521 -------------LHVDQ-----------------LKDFN-----IP-QAGGWGPWGPWGDCSRT 549

  Fly   696 CLYGQSRRLLEGSTGLRTLNRSCL-----NFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQV 755
            |           ..|::..:|.|.     |....|.||...|.:|||..|......|..:  .|.
  Rat   550 C-----------GGGVQFSSRDCTKPVPRNGGKYCEGRRTPFRSCNTKNCPHGSALTFRE--EQC 601

  Fly   756 CMQARKSD------------PELTGEGQQLPSTLDASCKIFCRTRTNG----TKSRRWTFPDGTT 804
            .....::|            |..||...:      ..||:.|:.|..|    .:.|   ..|||.
  Rat   602 AAYNHRTDLFKSFPGPMDWVPRYTGVAPR------DQCKLTCQARALGYYYVLEPR---VADGTP 657

  Fly   805 CKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMD--------SSFC--EARSVRPTRDSSDQES 859
            |     :|:..:.|:.|||....||....:..|.|        .|.|  ::.|.:..|.......
  Rat   658 C-----SPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGGNGSSCSKQSGSFKKFRYGYSDVV 717

  Fly   860 RQQTNRQRYAERQEG-----------KPQKNHY--ENEVAKRPS--------------------- 890
            .....|.....||:|           |.....|  ..|....||
  Rat   718 TIPAGRTHILVRQQGGSGLKSIYLALKLADGSYALNGEYTLMPSSTDVVLPGAVSLRYSGRTAAS 782

  Fly   891 -----YG------------QGNHINAPASPYKRRNYHKPYP-PEIPRPPP 922
                 :|            .||    |.:...|.::..|.| |..|||||
  Rat   783 ETLSGHGPLAQPLTLQVLVAGN----PQNVRLRYSFFVPRPVPSTPRPPP 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848	21/94 (22%)
		ZnMc_ADAMTS_like	331..543	CDD:239801	67/221 (30%)
		Reprolysin	332..545	CDD:279729	68/222 (31%)
		TSP1	683..741	CDD:214559	16/62 (26%)
Adamts4	NP_076449.1	Pep_M12B_propep	92..195	CDD:279848	32/127 (25%)
		Reprolysin	232..442	CDD:279729	70/232 (30%)
		ZnMc_ADAMTS_like	232..439	CDD:239801	68/229 (30%)
		ADAM_CR	452..523	CDD:301627	26/104 (25%)
		TSP1	545..589	CDD:214559	13/54 (24%)
		ADAM_spacer1	701..816	CDD:283607	16/118 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810