Protein Alignment stl and adamts8a

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_021332165.1
• Gene: adamts8a / 569618
• ZFINID: ZDB-GENE-060526-202
• Length: 940
• Species: Danio rerio
• Alignment Length: 691
• Identity: 172/691 - (24%)
• Similarity: 271/691 - (39%)
• Gaps: 161/691 - (23%)

  Fly   192 LERCFY-------RSPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLYQARVDKSGG 249
            |..|||       :....|:.||.  .:.|.|...|.:..|||..:...||.| ..|..|.|.
Zfish   110 LRDCFYTGTVNSEKESVVAVSLCH--GIHGTFITQGVEYFIHPKASVQTTGKH-FPQVHVIKR-- 169

  Fly   250 GYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRR 314
              ...|:.||||.:..|::.:           .|..:|:|.|          ......:.:|.:|
Zfish   170 --RAVSNSRTASLVFDQMKVD-----------SLVKESKLNS----------SEDEDSNMRRAKR 211

  Fly   315 YIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTL 379
            ::..|           .:|||.:..|    |.|.:.:    ..::..:||.::.....::.||:|
Zfish   212 FVSAA-----------RYIETLVVAD----ASMTRFY----GDEIKHYLLTVMAMAAQVFVHPSL 257

  Fly   380 GRRINFVLKRLEIWKSWD-PPGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDL 443
            ...::.|:.::.:.:..: .|.|..:..|.  |.:||.||:..||.|...|.|||.|::.|..|:
Zfish   258 KNAVSLVVVKMVVVEDEEVGPELSSNGGVA--LRNFCMWQQLFNPGSQRHPEHYDTAILFTREDI 320

  Fly   444 VTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDPTM 508
            ..|    .:...:|:|.|..||....||::.|....::.|.|:||:||.|.|.||..: :|:...
Zfish   321 CGY----KDCDTLGVADVGTMCDPKRSCSVIEDNGLQAAFTVSHELGHVLSMPHDDSK-NCEKWF 380

  Fly   509 -----HIMSPKLG--SGKVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFN 566
                 |.|:|...  :..:.||.||..|:.:|..:...:||.|......|    ....|||..|.
Zfish   381 GHLYGHTMAPFFVHLNKTLPWSPCSALYITEFFDNGHGDCLLDPPEMTIP----LAAELPGHTFG 441

  Fly   567 ANQQCMLRFGKNFMQASTQSKMEICRDLHCRQDG----------LPWTSHPALEGTECGPNMWCR 621
            .:|||...||..:...|.....:.|..|.||::|          |.|.     :||.||.:..||
Zfish   442 LDQQCQQAFGNKYTHCSNAPADQTCVQLWCREEGKIQCTTRNGSLHWA-----DGTPCGEDRRCR 501

  Fly   622 GGTCEARSSKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEW 686
            .|.|.:        ||::        ||..:|:                |::       ..||||
Zfish   502 EGLCLS--------SAME--------EAGEQKV----------------PVN-------GGWGEW 527

  Fly   687 SEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLN-FPSR----CIGRDRRFVTCNTPQCHKVPVQ 746
            .....|...|           ..|:...:|.|.: .|..    |:|:..::.:|||..|   |..
Zfish   528 GPWGPCSRTC-----------GGGVEFSHRECTSPVPQNGGLYCVGQRVKYQSCNTQTC---PED 578

  Fly   747 TINDFATQVCMQARKSDPELTGEG---QQLPSTLDAS----CKIFCRTR-TNGTKSRRWTFPDGT 803
            ....|..:.| :...||..:..:|   |.:|.....|    ||:.||.: :|..|.......|||
Zfish   579 HGKSFREEQC-EKYNSDRYMDIKGNIKQWIPKYSGVSPRDRCKLVCRAKGSNEFKVFEAKVVDGT 642

  Fly   804 TCKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMDS-SFC 843
            ||     .|:..:.|:.|:|.:..||....:..|:|. |.|
Zfish   643 TC-----GPDTTSICVQGQCIKAGCDQVIGSNEKLDKCSVC 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801	60/219 (27%)
		ADAMTS_CR_2	561..625	CDD:465496	23/73 (32%)
		TSP1	683..741	CDD:214559	15/62 (24%)
adamts8a	XP_021332165.1	Pep_M12B_propep	44..167	CDD:460254	17/59 (29%)
		ZnMc_ADAMTS_like	217..422	CDD:239801	60/219 (27%)
		ADAMTS_CR_2	436..506	CDD:465496	23/74 (31%)
		TSP1	533..576	CDD:214559	12/56 (21%)
		ADAMTS_CR_3	<619..685	CDD:437068	21/65 (32%)
		ADAMTS_spacer1	687..805	CDD:461796
		TSP1_ADAMTS	832..883	CDD:465950
		TSP1_ADAMTS	886..940	CDD:465950