DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stl and si:ch211-267e7.3

DIOPT Version :9

Sequence 1:	NP_001097423.1	Gene:	stl / 37619	FlyBaseID:	FBgn0086408	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	XP_696251.5	Gene:	si:ch211-267e7.3 / 567853	ZFINID:	ZDB-GENE-070912-265	Length:	963	Species:	Danio rerio

Alignment Length:	340	Identity:	74/340 - (21%)
Similarity:	101/340 - (29%)	Gaps:	103/340 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   683 WGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCL--------NFPSR-CIGRDRRFVTCNTP 738
            |||||..|.|...|           ..|:|:..|.||        |..|. |||..:::..|...
Zfish    53 WGEWSSWSTCSRTC-----------GGGVRSQERHCLQQRLTSTQNINSSFCIGPSKQYQLCTNQ 106

  Fly   739 QCHKVPVQTINDFATQVCMQ------ARKSDPELTGEGQQLPSTLDASCKIFCRTRTNGTKSRRW 797
            .|   |...|: |....|.|      :||....:........:..:..|.:.|.|.|.   .|:.
Zfish   107 PC---PNSRIS-FKQHQCSQFNAKAFSRKHYEWVPLYPDDYINISNKPCDLQCTTTTG---ERQL 164

  Fly   798 TFP--DGTTCKAKQHNPEDITY---CISGRCERFSCDNSTSNFFKMDS-SFCEARSVRPTRDSSD 856
            ..|  |||.|:       |..|   ||.|:|:...||....:...:|. ..|........|.|..
Zfish   165 LVPAHDGTFCR-------DGIYQGVCIEGQCQVVGCDGKLYSSKTIDKCGVCGGNGASCYRVSGT 222

  Fly   857 QE------------------------SRQQTNRQRYAERQEG-----------KPQKNHYENEVA 886
            ..                        .|::|........:.|           .||..|....|.
Zfish   223 YRKGITQLGYVFITNIPVGATDIQIIERRKTENILALSDEAGHFFFNGNSVIDNPQNFHVAGTVF 287

  Fly   887 K--RPS--YGQG-NHINAPA----------------SPYKRRNYHKPYPPEIPRPPPPASASLIA 930
            |  ||:  :..| .:|.|..                .|:....|..|..|..|....|....:..
Zfish   288 KYRRPANLFSDGFEYIMAQGPTQQALNVMYYNLNGKMPHITYEYTVPRAPAFPMTSTPEQPQISN 352

  Fly   931 LDRSSSSESEWVAHP 945
            |...:|.:|. ||.|
Zfish   353 LMSKTSRDSS-VAEP 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848
		ZnMc_ADAMTS_like	331..543	CDD:239801
		Reprolysin	332..545	CDD:279729
		TSP1	683..741	CDD:214559	19/66 (29%)
si:ch211-267e7.3	XP_696251.5	TSP1	53..109	CDD:214559	20/69 (29%)
		ADAM_spacer1	217..334	CDD:283607	17/116 (15%)
		TSP1	637..>660	CDD:214559
		TSP1	700..749	CDD:214559
		TSP1	752..806	CDD:214559
		TSP1	865..918	CDD:214559
		PLAC	928..959	CDD:285849
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13723
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000