Protein Alignment stl and adamts10

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_001116746.1
• Gene: adamts10 / 564734
• ZFINID: ZDB-GENE-081104-414
• Length: 1108
• Species: Danio rerio
• Alignment Length: 1118
• Identity: 253/1118 - (22%)
• Similarity: 378/1118 - (33%)
• Gaps: 337/1118 - (30%)

  Fly   113 EAEQHGGNPHQR-RQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTE 176
            |...||...|:| .:.:|.|.        |:...|.:....:..|.|.....|:...|    |.|
Zfish    62 EETSHGTVRHRRSTETQSAPE--------PQLYYQLSTSSTDLLLNLTLQGGLLSRQF----RVE 114

  Fly   177 ---NGTQFVEHSPQLLKRLERCFY--------RSPAAALDLCEPGNVRGVFQQNGSDLVIHPL-- 228
               .|.....|     ..|..|.|        .|.:.||..|  ..::||....|.:.:|.||
Zfish   115 YWKRGRLAWSH-----PYLPSCHYVGHLQHQPHSSSVALSNC--NGLQGVIVAGGEEYLIEPLVS 172

  Fly   229 -------PARFGTGTHVLYQ------ARVDKSGG------GYSEASSRRTASPLDSQLQFEPDAE 274
                   ..|.|. .||:|:      ..:|:|.|      |.|....:||..|..:|:
Zfish   173 AKNLTNEDGREGR-PHVVYKRSSLRYQNMDQSCGVIDEKPGKSYGWWQRTIKPSPNQM------- 229

  Fly   275 EFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFV 339
                      .:.||  ||:                          ||    :..|.|:||.:..
Zfish   230 ----------GRGQL--PLK--------------------------RS----VSRERFVETLVVA 252

  Fly   340 DSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRS 404
            |..:.::       :....:..::||::|.|..|:...:||..:|.|:.|| |....|.|.|..:
Zfish   253 DKMMVSY-------HGRRDIEQYILAVMNIVAKLFQDSSLGNAVNIVVTRL-ILLMEDQPTLEVN 309

  Fly   405 RDVENYLNSFCKWQEKL-------NPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVK 462
            ......|:||||||:.:       |...|....|:|.|:::|..|:..|......:  :|:|.|.
Zfish   310 HHAGKSLDSFCKWQKSILHRNGHGNAIPDNGIAHHDTAVLITRYDICIYKNKPCGT--LGLAPVG 372

  Fly   463 GMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISC----DPTMHIMSP--KLGSGKVT 521
            |||....||:|||.....:.|.:||||||..||.||....:|    ..|..:|:.  .:.:....
Zfish   373 GMCEPERSCSINEDIGLATAFTIAHEIGHTFGMNHDGVGNACGVRSQETAKLMAAHITMKTNPFV 437

  Fly   522 WSKCSRTYLEDFLMDPQAECLFD---RDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQAS 583
            ||.|||.|:.:||......||.:   :..|..|  .||    ||:.::|::||..::|..    |
Zfish   438 WSACSRDYITNFLDSGMGSCLNNVPPKQEFVYP--TTA----PGQAYDADEQCRFQYGVK----S 492

  Fly   584 TQSKM-EICRDLHCRQDG--LPWTSHPALEGTECGPNM----WCRGGTCEARSSKQGSYSALKSW 641
            .|.|. |:|.:|.|...|  ...:|.||.|||.|..:.    ||....|
Zfish   493 RQCKYGEVCSELWCMSKGNRCITSSIPAAEGTICQTSTIEKGWCYKRLC---------------- 541

  Fly   642 PPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLE 706
                :|..|..:                        |....||.||....|...|..|.|..:..
Zfish   542 ----VPYGTRPE------------------------GVDGGWGHWSPWEECSRTCGGGVSSSIRH 578

  Fly   707 GSTGLRTLNRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSD-------- 763
            ..:...|:.      ...|:|..:||.:||..:|   ||.: .||....|     ||
Zfish   579 CDSPRPTVG------GKYCLGERKRFRSCNIDEC---PVGS-QDFREIQC-----SDFDSVPFRG 628

  Fly   764 -----PELTGEGQQLPSTLDASCKIFCRTR-TNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGR 822
                 ....|.|.:       ||.:.|... .|....|.....|||.|:     .:.:..|::|.
Zfish   629 KFYTWKPYRGGGVK-------SCSLNCLAEGYNFYTERAPAVVDGTPCR-----DDSLDVCVNGE 681

  Fly   823 CERFSCDNSTSNFFKM--------DSSFCEA-RSVRPTRDSSDQESRQQTNR----QRYAERQEG 874
            |:...||....:..:.        |.|.|:. ..|  ..||..:...::..|    ..:...||.
Zfish   682 CKHVGCDRILGSDVREDRCRVCGGDGSSCQVIEGV--FNDSLSEGGYEEVVRIPKGSVFIHIQEL 744

  Fly   875 KPQKNHYENEVAKRPSYGQGNHINAPAS-PYKRR--------NYHKP-YPPEIPRPPPPASASLI 929
            ....|:.   |.|  |.|....||...: ...||        :|.:| ..||......|.:.:||
Zfish   745 NISLNYL---VLK--SKGDQYFINGKLTIDTPRRFDIAGGTFHYRRPANEPETLEALGPTNMTLI 804

  Fly   930 AL------------------DRSSSSESEWVAHPGCHSNCMTDSKG---VQGVTSRLTGVESI-- 971
            .:                  .|...|...|  |....|.|.....|   ||.|..:.....|:
Zfish   805 VMVLVREENPGILYRFNPPVSRDPLSSYSW--HYTSWSRCSALCAGGVQVQQVVCKKQADLSVVY 867

  Fly   972 -QLCSYR-----------IQPCERLQTAAEYAE--QTC---ARYRQKV--RGLSGHGAQI----- 1012
             ..|..:           .:||.......:::|  ::|   .|.|:.:  |.:|....::
Zfish   868 NHFCDKKNKPKDKKRPCNQEPCPPTWWTGDWSECSRSCNGGVRTREVLCKRKMSVTEEKVLDDTA 932

  Fly  1013 ----SASIDEPDRS--------------CRVGCQDEFIKYRYYLV---NGRNGHFPPGTRC---- 1052
                ..|:.||..:              |..||..   .|||.::   :|.||...|.:.|
Zfish   933 CTTTRPSVTEPCNNHTCPPEWHALDWSECTPGCGP---GYRYRVILCRSGDNGETLPESECPKQS 994

  Fly  1053 SPVGKRYCVYGRC 1065
            .|..:..|...||
Zfish   995 RPTTRVRCNIQRC 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848	24/103 (23%)
		ZnMc_ADAMTS_like	331..543	CDD:239801	68/224 (30%)
		Reprolysin	332..545	CDD:279729	69/228 (30%)
		TSP1	683..741	CDD:214559	15/57 (26%)
adamts10	NP_001116746.1	Pep_M12B_propep	71..189	CDD:279848	30/137 (22%)
		Reprolysin	244..462	CDD:279729	69/227 (30%)
		ZnMc_ADAMTS_like	244..459	CDD:239801	68/224 (30%)
		TSP1	555..607	CDD:214559	16/60 (27%)
		ADAM_spacer1	711..823	CDD:283607	22/118 (19%)
		TSP1	893..950	CDD:214559	9/56 (16%)
		PLAC	1074..1106	CDD:285849

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13723
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910