DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stl and paplna

DIOPT Version :9

Sequence 1:	NP_001097423.1	Gene:	stl / 37619	FlyBaseID:	FBgn0086408	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	376	Identity:	79/376 - (21%)
Similarity:	127/376 - (33%)	Gaps:	108/376 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   676 LPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLNFPS----RCIGRDRRFVTCN 736
            :.|...||||||.         ||:..|...|...:||  |.|:...:    .|:|.|:.:.:||
Zfish    17 MQGIGDNWGEWSS---------YGECSRSCGGGVTMRT--RRCVTHRTDGGHSCVGPDKSYRSCN 70

  Fly   737 TPQCHKVPVQTINDFATQVCMQARKSD---------PELTGEGQQLPSTLDASCKIFCRTR-TNG 791
            ...|    .:...||..:.|.|...:|         |...||.         .|::.|..| .|.
Zfish    71 IQDC----PEGSRDFREEQCSQFDGTDFQGKRYKWLPYYGGEN---------PCELNCIPRGENF 122

  Fly   792 TKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMDSSF-C--EARSVRPTRD 853
            ...::.:..|||.|:     |.....|:.|.|:|..||:...:..:.|:.. |  :.:|....::
Zfish   123 YYRQKSSVVDGTPCR-----PGGKDICVDGLCKRLGCDHMLESPQEEDACLQCGGDGQSCSRLKN 182

  Fly   854 SSDQESRQQTNRQRY--------AERQEGKPQKNHYENEVAKRPSYGQGN---HINAPAS----- 902
            |....:..:...|.:        ...:|..|.:|:...:..:...|..|:   .::..||
Zfish   183 SFSMRNLPKGYNQMFIIPVGATTISIKETLPTRNYLAIKNLRGEYYLNGHWVIDLSRAASIAGTV 247

  Fly   903 -PYKRRNYHKPYPPEIPRPPP---PASASLIA------------LDRSSSSE------SEWVAHP 945
             .|:|....:..|..|....|   |....||.            |....|:|      ..|.|
Zfish   248 LHYQRGREGEKSPEMITGRGPTTEPLVIELITQEVNEGVDYEYYLPNGGSTEGYYWSYGSWSA-- 310

  Fly   946 GCHSNCMTDSKGVQGVTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCA 996
             |...|.:      |..|||.      .|::..:         .|::..||
Zfish   311 -CSKECGS------GYQSRLV------FCTFEDE---------AYSDYLCA 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848
		ZnMc_ADAMTS_like	331..543	CDD:239801
		Reprolysin	332..545	CDD:279729
		TSP1	683..741	CDD:214559	18/61 (30%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559	19/65 (29%)
		ADAM_spacer1	181..293	CDD:310520	17/111 (15%)
		TSP1	303..356	CDD:214559	12/61 (20%)
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449
		IGc2	960..1022	CDD:197706
		I-set	1039..1121	CDD:333254
		PLAC	1142..1173	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900