DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment stl and Wfikkn1

DIOPT Version :9

Sequence 1:NP_001097423.1 Gene:stl / 37619 FlyBaseID:FBgn0086408 Length:1136 Species:Drosophila melanogaster
Sequence 2:NP_001123248.1 Gene:Wfikkn1 / 363555 RGDID:1565835 Length:552 Species:Rattus norvegicus


Alignment Length:512 Identity:96/512 - (18%)
Similarity:134/512 - (26%) Gaps:265/512 - (51%)


- Green bases have known domain annotations that are detailed below.


  Fly   483 FVVAH---------EIGHNLGMRHDAKEISCDPTMHIMSPKLGSGKVTW----SKCSRTYLEDFL 534
            ||:.|         |.|.:.||        | |..  :||.|      |    |.|.|       
  Rat    14 FVLIHLTSETNLLPEPGSHPGM--------C-PNQ--LSPHL------WVDAQSTCER------- 54

  Fly   535 MDPQAECLFDRDSFAGPWDHTAGGRLPGERFNAN----QQCM-LRFGKNFMQASTQSKMEICRDL 594
                 ||..|:|..|            .|:...|    |.|: .||...  ..:|......|.|.
  Rat    55 -----ECTRDQDCAA------------SEKCCTNVCGLQSCVAARFPSG--GPATPETAASCEDF 100

  Fly   595 HCRQDGLPWTSHPALEGTECGPNMW-----CRGGTCEARSSKQGSYSA----------------- 637
            .|.|           :|:.|  ::|     ||   |..|..|:.|::.                 
  Rat   101 QCPQ-----------QGSNC--DIWDGQPVCR---CRDRCEKEPSFTCASDGLTYYNRCYMDAEA 149

  Fly   638 --------------LKSWPPEH--IPEATHEKIIRHEPNR--IPPLLHDYN-------------P 671
                          :.||||..  .||.|    .|..|..  :||.|  ||             .
  Rat   150 CLRGLHLHVVPCKHILSWPPSSPGPPETT----ARPTPGAAPMPPAL--YNSPSPQAVHVGGTAS 208

  Fly   672 MDNELPGSPSNWGEWSEPS------------------------------ACESGCLYGQSRR--- 703
            :..::.|.|.....|.:.|                              ..|...||..:.|   
  Rat   209 LHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNAQLEDAGLYTCTARNAA 273

  Fly   704 -LLEGSTGLRTLNR-----------------------------------------SCLNFPS-RC 725
             ||.....|..|.|                                         ||:.||: :|
  Rat   274 GLLRADFPLSVLQRATTQDRDPGVLALAECQPDTQACVGPPTPHHVLWRFDPQRGSCMTFPALKC 338

  Fly   726 IGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELTGEGQQLPSTLDASCKIFCRTRTN 790
            .|..|.|.|                  .:.|.||....|   |:...|| .:...|:.:      
  Rat   339 DGAARGFET------------------YEACQQACVRGP---GDVCALP-PVQGPCQGW------ 375

  Fly   791 GTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERF---SCDNSTSNFFKMDSSFCE 844
               ..||.:           :|      :..:|..|   .|:.:::||...:|  ||
  Rat   376 ---EPRWAY-----------SP------LLQQCHPFIYSGCEGNSNNFESRES--CE 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stlNP_001097423.1 Pep_M12B_propep <155..239 CDD:279848
ZnMc_ADAMTS_like 331..543 CDD:239801 18/72 (25%)
Reprolysin 332..545 CDD:279729 18/74 (24%)
TSP1 683..741 CDD:214559 20/133 (15%)
Wfikkn1NP_001123248.1 WAP 34..80 CDD:278522 20/86 (23%)
KAZAL_FS 124..159 CDD:238052 2/34 (6%)
I-set 196..284 CDD:254352 11/87 (13%)
Ig_3 204..284 CDD:143242 11/79 (14%)
KU 311..356 CDD:294074 12/62 (19%)
KU 361..413 CDD:197529 14/79 (18%)
NTR_like 431..541 CDD:295338
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3538
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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