Protein Alignment stl and AdamTS-B

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_572247.2
• Gene: AdamTS-B / 31490
• FlyBaseID: FBgn0029791
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 1150
• Identity: 279/1150 - (24%)
• Similarity: 407/1150 - (35%)
• Gaps: 377/1150 - (32%)

  Fly    77 IFGSRSPE-EAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQR-RQRRSLPSEDGNG-- 137
            ::|..|.| .|.|.:||...:..|:......:.:...|.:      |:| ||||||.||....
  Fly    33 LYGLHSDELVAGEGQLVVPRRVHPDGAFMTHQLEYAHELD------HRRHRQRRSLNSEHDTQAA 91

  Fly   138 ------PLPPEEEEQEAGEDVEARLQLQQ---SPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLE 193
                  ||        |.|.:...|....   :|.|:.:......||        .||...:.|
  Fly    92 DLHLLLPL--------ANETLHLELMAHSYFLAPNLVVERHRRDLRT--------RSPLTTRHL- 139

  Fly   194 RCFYR-----SPAAALDLCEPGNVRGVFQQNGSDLVIHPL----PARFGTGTHVLYQ-------- 241
            .|.:.     .||..:.:.....:.|..:..|::..|.|.    |.......||::|
  Fly   140 NCHFHGKVRGQPATNVAISTCAGLVGHIRTAGNEYFIEPSKEHEPHPVNGHPHVVFQRSSVKPKH 204

  Fly   242 --------ARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQ 298
                    .|..|||.| :|.|:..|                 .|||||:..:.:.|:..:::.|
  Fly   205 SLRKRNKRKRGGKSGSG-AEVSNCGT-----------------REPRRRMETRLEWQARGKVKVQ 251

  Fly   299 -----PRHHHPHQHHQQRRR-----RYIGDAPRSRW------------SDIPEE-------LFIE 334
                 .||||.|.||..:.:     :.|...|.:::            ::||..       ..:|
  Fly   252 GGRQIRRHHHHHHHHHHKHKYRHHQQKISRVPHTKFKYETQFQTEPDHAEIPRRRRSISSPRHVE 316

  Fly   335 TAIFVDSDLYA-HMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKR-LEIWKSWD 397
            |.|..|:.:.| |...|          .:||.::|.|..||..|::|..|..|:.| :::.:...
  Fly   317 TLIVADATMSAFHRDLN----------GYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEEES 371

  Fly   398 PPGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVK 462
            ...|..:::.:..|:.||.||.|||..|:.||.|:|.|:::|..::..     .|...:|:|.|.
  Fly   372 QLQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICA-----NNCMTLGLANVG 431

  Fly   463 GMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISC----DPTMHIMSPKLGSG--KVT 521
            |||....||::||.........:.||:|||.||.||..:|.|    .|.:|||:|..|:.  :|.
  Fly   432 GMCKPKQSCSVNEDNGIMLSHTITHELGHNFGMFHDTAKIGCHPRVGPIVHIMTPTFGADTLQVC 496

  Fly   522 WSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQS 586
            ||.|||.|:..||.....|||.|..:....:::|  |.|||.|:||..||.|:|     ..:|.|
  Fly   497 WSNCSRKYITHFLDQGLGECLDDPPTPLDEYNYT--GELPGMRYNARGQCRLQF-----NLTTDS 554

  Fly   587 KM-------EICRDLHCRQDGLPWTSH--PALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWP 642
            ::       |.|..|.|:.:| ...:|  |...||.||.|.||:.|.|
  Fly   555 EVGACSAPHEFCSTLWCKVNG-ECVTHMRPTAPGTLCGRNKWCQNGKC----------------- 601

  Fly   643 PEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEG 707
                        :|.|                ||......||:|||.|.|...|
  Fly   602 ------------VRRE----------------ELAAVNGGWGDWSEWSECSRSC----------- 627

  Fly   708 STGLRTLNRSCLN-FPSR----CIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELT 767
            ..|:.|..|.|.| .|:.    |||..:|:..|....|   |.:. ..|..|.|  ||..:....
  Fly   628 GGGVSTQQRECDNPVPANGGVFCIGERKRYKICRKRPC---PAEE-PSFRAQQC--ARFDNVSYQ 686

  Fly   768 GEGQQLPSTLDAS--CKIFCRTRTNGTKSRRW--TFPDGTTCKAKQHNPEDITYCISGRCERFSC 828
            |...:.....|.:  ||:|| :..:.|....|  |..|||.|....:|     .||.|.|::..|
  Fly   687 GATYKWLPFFDKNNPCKLFC-SDVDDTIIANWGATVLDGTPCTLGTNN-----MCIDGICKKVGC 745

  Fly   829 DNSTSNFFKMDSSFCEARSVRPTR-----DSSDQESRQQTNRQRYAERQEGK----------PQK 878
            |      :.:||      .|:..|     .|.||   .|..|:.|.:....|          |.:
  Fly   746 D------WIVDS------EVQDDRCGVCGGSGDQ---CQPVRETYTDPFAAKDGAYVEIVTIPAR 795

  Fly   879 NHY--ENEVAKRPSY-----GQGNH---------INAPA--------SPYKRRNYHKPYPPEIPR 919
            ..:  ..|:|..|.:     |.|..         |:.|.        |.|.|.:..:..  .||:
  Fly   796 ARHILIRELANSPHFLAIATGDGGDRFYLNGDSLISMPGEFEIAGAESLYDRVDEQETI--TIPQ 858

  Fly   920 PPPPASASLIALDRSSSSE------------------------SEWVAHPGCHSNCMTDSKGVQG 960
             |...|.||.|:.|.:.|.                        |.|.|   |.::|   ..|||
  Fly   859 -PIQHSISLYAIVRGNESNAGIFYEFTLPALNVTAGRQFQWRLSNWTA---CSASC---GGGVQ- 915

  Fly   961 VTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCARYRQKVRGLSGHGAQIS--------ASID 1017
                                         :.|..|..          :|..:.        |...
  Fly   916 -----------------------------HREPICQE----------NGKALGDTLPCWTHAKNK 941

  Fly  1018 EPDRSCRVGCQDEFIKYRYYLVNGRNGHFPPG------TRCSPVG 1056
            .|.|..| ||.|:...          .|:.||      ..|.|||
  Fly   942 RPARQSR-GCGDQPCP----------AHWWPGPWQFCPVTCRPVG 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848	17/95 (18%)
		ZnMc_ADAMTS_like	331..543	CDD:239801	73/219 (33%)
		Reprolysin	332..545	CDD:279729	74/220 (34%)
		TSP1	683..741	CDD:214559	19/62 (31%)
AdamTS-B	NP_572247.2	Pep_M12B_propep	78..194	CDD:279848	28/132 (21%)
		ZnMc_ADAMTS_like	314..518	CDD:239801	73/218 (33%)
		Reprolysin	315..521	CDD:279729	75/220 (34%)
		ADAM_CR	<558..602	CDD:301627	16/73 (22%)
		TSP1	614..666	CDD:214559	20/65 (31%)
		ADAM_spacer1	773..886	CDD:283607	22/115 (19%)
		TSP1	901..956	CDD:214559	18/101 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13723
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910