Protein Alignment stl and Adamtsl3

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_001101003.2
• Gene: Adamtsl3 / 308787
• RGDID: 1305155
• Length: 1705
• Species: Rattus norvegicus
• Alignment Length: 576
• Identity: 120/576 - (20%)
• Similarity: 174/576 - (30%)
• Gaps: 231/576 - (40%)

  Fly   630 SKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPM-------DNELPGSPSNWGEWS 687
            |.|||:          :.:.|.|:.          |.:.|:..       |.:..|:...||:||
  Rat    53 SPQGSF----------LEDTTGEQF----------LTYRYDDQTSRNAHSDEDKDGNWDAWGDWS 97

  Fly   688 EPS-ACESGCLYGQSRRLLEGSTGLRTLNRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDF 751
            :.| .|..|..| ..||.|.|               ..|.|::.|:.||:...|   |... .||
  Rat    98 DCSRTCGGGASY-SLRRCLTG---------------RNCEGQNIRYKTCSNHDC---PADA-EDF 142

  Fly   752 ATQVCMQARKSDPELTGEGQQ-LPSTLD--ASCKIFCRTRTNGTKSRRWTFP---DGTTCKAKQH 810
            ..|.|  :..:|.:..|...: :|...|  |.|.:.|..|  |........|   |||.|
  Rat   143 RAQQC--SAYNDVQYQGHYYEWIPLHNDPAAPCALKCHAR--GQSLVVELAPKVLDGTRC----- 198

  Fly   811 NPEDITYCISGRCERFSCDNSTSNFFKMDS--------SFCE----------------------- 844
            |.:.:..||||.|:...||....:..|.|:        |.|.
  Rat   199 NADTLDMCISGICQTVGCDRQLGSSAKKDNCGVCAGDGSTCRLVRGQTKVHLSPEKKEENVIAVP 263

  Fly   845 --ARSVRPT---------RDSSDQESRQQ---------------TNRQRYAERQEGKPQ------ 877
              :||||.|         ...:.|.||.:               ...|:.|:||..|..
  Rat   264 LGSRSVRITVKGPALLFIESKTLQGSRGEHSFNSPGVFVVENTTIEFQKGADRQTFKIAGPLMAD 328

  Fly   878 ---KNHYENEVAK---------RP---------------SYGQGNHINAPAS---PYKR--RNYH 910
               |..|  .|||         :|               :.|.|..:|:...   ..||  .:::
  Rat   329 FIFKTRY--TVAKGSVVQFFFYQPISHQWRQTDFFPCTVTCGGGYQLNSAECMDIRLKRVVPDHY 391

  Fly   911 KPYPPEIPRPPPPASASLIALDRSSSSES--------------EWVAHP--GCHSNCMTDSKGVQ 959
            ..|.||..:|.|....  .::|...||:.              .|..:|  .|..:|   ..|:|
  Rat   392 CHYYPENVKPKPKLKE--CSMDPCPSSDGFKEIMPYDHFQPLPRWEHNPWTACSVSC---GGGIQ 451

  Fly   960 ---------GVTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCARYRQKVRGLSGHGAQISAS 1015
                     .:.:.:..||..: |.|..:|         ...|||..:
  Rat   452 RRSFVCVEESMHAEILQVEEWK-CMYAPKP---------KVMQTCNLF----------------- 489

  Fly  1016 IDEPD------RSCRVGCQDEFIKYRYYLVNGRNGHFPPGTRCSPVGKRY----CV 1061
             |.|.      ..|.|.| ...::||..|.....|....|  |:|..|.:    ||
  Rat   490 -DCPKWIAMEWSQCTVTC-GRGLRYRVVLCINHRGQHVGG--CNPQMKLHIKEECV 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848
		ZnMc_ADAMTS_like	331..543	CDD:239801
		Reprolysin	332..545	CDD:279729
		TSP1	683..741	CDD:214559	17/58 (29%)
Adamtsl3	NP_001101003.2	TSP1	90..136	CDD:214559	18/64 (28%)
		TSP1	438..>458	CDD:214559	5/22 (23%)
		TSP1	498..>527	CDD:214559	7/29 (24%)
		TSP1	583..>603	CDD:214559
		TSP1	720..773	CDD:214559
		TSP1	839..894	CDD:214559
		Ig	942..1006	CDD:299845
		Ig	1223..1291	CDD:143165
		IG_like	1313..1392	CDD:214653
		IGc2	1329..1387	CDD:197706
		TSP_1	1502..1557	CDD:278517
		PLAC	1673..1703	CDD:285849

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900