Protein Alignment stl and Adamts8

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_001414107.1
• Gene: Adamts8 / 300475
• RGDID: 1308511
• Length: 905
• Species: Rattus norvegicus
• Alignment Length: 711
• Identity: 177/711 - (24%)
• Similarity: 273/711 - (38%)
• Gaps: 179/711 - (25%)

  Fly   192 LERCFY-------RSPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLYQARVDKSGG 249
            |..||:       |...||:.||  |.:.|.|...|.:..|.|.    |.|..:....|:.:.|.
  Rat    99 LRGCFFSGTVNGERESLAAMSLC--GGLSGSFLLAGEEFTIQPQ----GAGDSLDQPHRLQRWGP 157

  Fly   250 GYSEASSRRTAS---PLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQ---PRHHHPHQHH 308
            |.........|:   ||...|::|.:..:....|||...:.:.:....||.:   .|...|....
  Rat   158 GQRREDPGLAAAEVFPLPQGLEWEVEMGDGQGQRRRDNEEDRERDKEGLRKETEDSREVTPPFGS 222

  Fly   309 QQRRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLL 373
            :.|.:|::.:|           .|:|..:..|:.:.|.    :.|:.::.:    |.:::....:
  Rat   223 KTRSKRFVSEA-----------RFVEILLVADASMAAF----YGTDLQNHI----LTVMSMAARI 268

  Fly   374 YHHPTLGRRINFVLKRLEI--WKSWDPP-----GLVRSRDVENYLNSFCKWQEKLNPFSDADPLH 431
            |.||::...||.|:.::.|  .:.|.|.     ||.        |.:||.||.:.|..||..|.|
  Rat   269 YKHPSIRNSINLVVVKVLIVEEEGWGPEVSDNGGLT--------LRNFCSWQRRFNKPSDRHPEH 325

  Fly   432 YDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMR 496
            ||.|::.|..:...  ||: ....:|||.|..:|....||::.:.:..::.:.:|||:||.|.|.
  Rat   326 YDTAILFTRQNFCR--KGE-QCDTLGMADVGTICDPNKSCSVIKDEGLQAAYTLAHELGHVLSMP 387

  Fly   497 HDAKEISCDPTMHIMSPKLGSGK--------------VTWSKCSRTYLEDFLMDPQAECLFDRDS 547
            ||..:    |.:.:..|   .||              :.||.||..||.:.|.|...:||.|..:
  Rat   388 HDDSK----PCVRLFGP---MGKYHMMAPFFIHVNKTLPWSPCSAVYLTELLDDGHGDCLLDAPT 445

  Fly   548 FAGPWDHTAGGRLPGER--FNANQQCMLRFGKNFMQASTQSKMEICRDLHCR------------Q 598
            ...|.  ..|  |||..  :..:|||...||.:|......|..:||..|.||            .
  Rat   446 SVLPL--PTG--LPGHSTLYELDQQCKQIFGPDFRHCPNTSVEDICVQLWCRHRDSDEPICHTKN 506

  Fly   599 DGLPWTSHPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIP 663
            ..|.|.     :||.|||...|..|:|..|...:.             |:|..:
  Rat   507 GSLLWA-----DGTPCGPGHLCLDGSCVLREEVEN-------------PKAVVD----------- 542

  Fly   664 PLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLN-FPSR--- 724
               .|:.|           ||.|            ||..|...|  |::..||.|.| .|..
  Rat   543 ---GDWGP-----------WGPW------------GQCSRTCGG--GIQFSNRECDNPAPQNGGR 579

  Fly   725 -CIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARK-SDPELTGEG-QQLPSTLDAS----CK 782
             |:|...::.:|.|.:|   |... ..|..|.|.:... :..:|.|.. |.:|.....|    ||
  Rat   580 FCLGERVKYQSCKTEEC---PPNG-KSFREQQCEKYNAYNHTDLDGNFLQWVPKYSGVSPRDRCK 640

  Fly   783 IFCRTRTNGTKSRRWTFP----DGTTCKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMD 839
            :|||.|   .:|....|.    |||.|     .|:.:..|:.|:|.:..||:..::..|:|
  Rat   641 LFCRAR---GRSEFKVFETKVIDGTLC-----GPDTLAICVRGQCVKAGCDHVVNSPKKLD 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801	62/232 (27%)
		ADAMTS_CR_2	561..625	CDD:465496	23/77 (30%)
		TSP1	683..741	CDD:214559	17/62 (27%)
Adamts8	NP_001414107.1	None