Protein Alignment stl and Adamts17

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_218753.6
• Gene: Adamts17 / 293004
• RGDID: 1308783
• Length: 1122
• Species: Rattus norvegicus
• Alignment Length: 1146
• Identity: 260/1146 - (22%)
• Similarity: 395/1146 - (34%)
• Gaps: 358/1146 - (31%)

  Fly    60 LDKNTLVGHLREHERALIFGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQR 124
            ||..|:||                :.|.:.::|...:.||::   :..:..||.|     ...|.
  Rat    21 LDPGTVVG----------------DAAADVEVVLPRRLRPDD---VHLQLLPGAA-----GLRQW 61

  Fly   125 RQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRR-----------TENG 178
            |:.|:.|.:...||          ||    |..|...|....|.::.:||           .|.|
  Rat    62 RRPRASPGDPRAGP----------GE----RALLLHLPAFGRDLYLQLRRDLRFLSPGFEVEEAG 112

  Fly   179 TQFVEHSPQLLKRLERCFYRSPA-------AALDLC-EPGNVRGVFQQNGSDLVIHPLPARFGTG 235
            .......|     .|.|||....       .:|..| ..|.:.|:.|.....:.|.||
  Rat   113 VSGRSGHP-----AELCFYSGQVLGHPGSLVSLSACGAAGGLVGLIQLEQELVFIQPL------- 165

  Fly   236 THVLYQARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPR 300
                     :.|||.:    |||.                 :..||:..:.|.|.:.:.   .||
  Rat   166 ---------NNSGGPF----SRRE-----------------HLIRRKWSSTSGLATKVE---GPR 197

  Fly   301 HHHPHQHHQQRRRRYIGDAPRSRWSDI--PEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFL 363
            .|......::.|:..:....|.|.:.|  ..|..:||.:..|:|:..:       :.......|:
  Rat   198 QHCKVVTEEKPRKGKLSWDWRERRNAIRLTNEHTVETLVVADADMVQY-------HGAEAAQRFI 255

  Fly   364 LAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKWQEK-------- 420
            |.::|.|..::.|.:||.:||..:.:|.:.:. .|..|......|..|.|||.||.:
  Rat   256 LTVMNMVYNMFQHQSLGIKINIQVTKLVLLRQ-RPAKLSIGHHGERSLESFCHWQNEEYGGARYL 319

  Fly   421 ---LNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESV 482
               ..|....|....|.|:.:|..|...:.....::  ||:|.:.|:|::...|.:.|.......
  Rat   320 GNNQVPGGKDDTPPVDAAVFVTRTDFCVHKDEPCDT--VGIAYLGGVCSAKRKCVLAEDNGLNLA 382

  Fly   483 FVVAHEIGHNLGMRHDAKEISCDPTMHIMSPKLGSGK----VTWSKCSRTYLEDFLMDPQAECLF 543
            |.:|||:||||||.||....||....||||.:...|:    ::||.|||..||:||....:.||.
  Rat   383 FTIAHELGHNLGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLL 447

  Fly   544 ---DRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQSKME--ICRDLHCRQDGLPW 603
               .|...|....|    :|||..::||:||.:.||.|   |:....||  :|..|.|..:|  .
  Rat   448 ITDPRSQHALRLPH----KLPGMHYSANEQCQILFGTN---ATFCKNMEHLMCAGLWCLVEG--D 503

  Fly   604 TS-----HPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWP-PEHIPEATHEKIIRHEPNRI 662
            ||     .|.|:|||||.:.|||.|.|.:::            | |||:
  Rat   504 TSCKTKLDPPLDGTECGADKWCRAGECVSKT------------PIPEHV---------------- 540

  Fly   663 PPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLNFP----- 722
                             ..:|..||..|.|...|           .||.|...|.|.|.|
  Rat   541 -----------------DGDWSPWSAWSMCSRTC-----------GTGARFRQRKCDNPPPGPGG 577

  Fly   723 SRCIGRDRRFVTCNTPQCHK-VPVQTINDFATQVCMQARKSDPELTGEGQQLPSTL---DASCKI 783
            :.|.|.......|....|.| ||     .|..|.|    ::...|:.:.:.|.:.:   |..|::
  Rat   578 THCQGASVEHAACENLPCPKGVP-----SFRDQQC----QAHDRLSSKKRGLLTAMVVDDKPCEL 633

  Fly   784 FCRTRTNGTKSRRWTFP--------DGTTCKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMD- 839
            :|...  |.:|     |        |||.|     .|.:...|:.|||::..||....:..|.|
  Rat   634 YCSPL--GKES-----PLLVADRVLDGTPC-----GPYETDLCVYGRCQKIGCDGIIGSAAKEDR 686

  Fly   840 -----------------------SSFCE-------ARSVRPTRD-------SSDQESRQQTNRQ- 866
                                   :.:.|       ||.:|...|       :....|::..|..
  Rat   687 CGVCSGDGKTCRVVKGDFSHSRGTGYIEAVVIPAGARRIRVVEDKPAHSFLALKDSSKRSINSDW 751

  Fly   867 ---------------RYAERQEGKPQKNHYENEVAKRPSYGQGNHINAPASPYKRRNYHKPYPPE 916
                           ||..|       ..:|...||.|:...   ::.....:..:||...|...
  Rat   752 KIELPGEFQIAGTIVRYVRR-------GLWEKFSAKGPTTVP---LHLMVLLFHDQNYGIHYEYT 806

  Fly   917 IPRPPPPASASLIALDRSSSSESE----------WVAHPGCHSNCMTDSKGVQGVTSRLTGVESI 971
            ||            :::|:.::||          |.     ||       |.:|.:.:..|.|..
  Rat   807 IP------------VNQSTENQSEPAKPQDALFLWT-----HS-------GWEGCSVQCGGGERR 847

  Fly   972 QLCSYRIQPCERL--QTAAEYAEQTC---ARYRQKVRGLSGHGAQ---ISASIDEPDRSCRVGCQ 1028
            .:.|     |.|:  :|.....:..|   :|...:||..:.|..|   ::........:|..|.|
  Rat   848 TIVS-----CTRIVNKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVAGQWSPCSATCEKGIQ 907

  Fly  1029 DEFIKYRYYLVNGRNGHFPPGTRCS---PVGKRYCVYGRCL 1066
            ...:...|.|.||.:....| ..||   |...:.|....||
  Rat   908 HREVTCVYQLQNGTHVTTRP-IYCSEPRPTPVQSCEGQDCL 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848	21/102 (21%)
		ZnMc_ADAMTS_like	331..543	CDD:239801	65/226 (29%)
		Reprolysin	332..545	CDD:279729	66/230 (29%)
		TSP1	683..741	CDD:214559	16/62 (26%)
Adamts17	XP_218753.6	Pep_M12B_propep	61..179	CDD:279848	34/173 (20%)
		AANH_like	168..>244	CDD:294206	22/99 (22%)
		Reprolysin	230..447	CDD:279729	65/226 (29%)
		ZnMc_ADAMTS_like	230..447	CDD:239801	65/226 (29%)
		TSP1	544..596	CDD:214559	16/62 (26%)
		ADAM_spacer1	698..808	CDD:283607	17/119 (14%)
		TSP_1	893..946	CDD:278517	12/53 (23%)
		TSP1	950..>981	CDD:214559
		TSP1	1001..1053	CDD:214559
		PLAC	1080..1106	CDD:285849

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810