Protein Alignment stl and Adamts2

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_001382353.1
• Gene: Adamts2 / 287899
• RGDID: 1565950
• Length: 1212
• Species: Rattus norvegicus
• Alignment Length: 1185
• Identity: 267/1185 - (22%)
• Similarity: 400/1185 - (33%)
• Gaps: 348/1185 - (29%)

  Fly    76 LIFGSRSPEEAPEF--KLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPSEDGNGP 138
            |:..:.:|...|.:  :.:.....|.:.|.||.......|..:.|     .|.||:.|.:...
  Rat    39 LVAATETPGGPPGYGAERILAVPVRTDAQGRLVSHVVSLETARAG-----VRARRAAPVQTSG-- 96

  Fly   139 LPPEEEEQEAGE--------DVEARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERC 195
            ||...|:...|.        ..:..|:|:.:.:|:........:.|.|...||      ..|..|
  Rat    97 LPGGAEQDPGGRLFYNLTVFGRDLHLRLRPNARLVAPGATVEWQGETGDTRVE------PLLGTC 155

  Fly   196 FY--------RSPAAALDLCEPGNVRGVFQQNGSDLVIHPL-------PARFGTGTHVLYQARVD 245
            .|        ::.:.||..|:  .:.|:.:....:..|.||       .|..|. .||:|
  Rat   156 LYVGDVADLPKTSSVALSNCD--GLAGLIRMEEEEFFIEPLEKGQTDQEAEQGR-VHVVY----- 212

  Fly   246 KSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQ 310
                       ||..:|....:. .|.|.:....:..|.:.|:....|..|.        ...::
  Rat   213 -----------RRPPTPKPPPVG-GPQALDTGASQGNLDSLSRALGVLEERI--------NSSRR 257

  Fly   311 RRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLY-----AHMQKNFPTNTESKVVSFLLAMINGV 370
            |.||:..|          ::..||..:.||..:.     .|:||            :||.::|.|
  Rat   258 RVRRHATD----------DDYNIEVLLGVDDSVVQFHGKEHVQK------------YLLTLMNIV 300

  Fly   371 QLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKW---QEKLNPFSDADPLHY 432
            ..:||..:||..||.||.|:.:........|:...:....|.:.|:|   |:|  |.:|.|..|
  Rat   301 NEIYHDESLGAHINVVLVRIILLSHAKSMSLIEIGNPSQSLENVCRWAYLQQK--PDTDHDEYH- 362

  Fly   433 DHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRH 497
            |||:.||..|.     |.:..|  |.|.|.|||..:.|||:|....|.|.||||||.||.|||.|
  Rat   363 DHAIFLTRQDF-----GPSGMQ--GYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEH 420

  Fly   498 DAKEISCDPTMH---IMSPKLGSG--KVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAG 557
            |.:...|...:.   ||:|.:.:.  :..||:||:..|..:|  ...:||.| |.||..|  .|.
  Rat   421 DGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYL--HSYDCLRD-DPFAHDW--PAL 480

  Fly   558 GRLPGERFNANQQCMLRFGKNFMQASTQSKMEICRDLHCRQDGLPW----TSHPALEGTECGPNM 618
            .:|||..::.|:||...||..:|..:.....:.|:.|.|.....|:    ...|.|:||.|.|..
  Rat   481 PQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGK 545

  Fly   619 WCRGGTCEARSSKQGSYSALKSW-PPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSN 682
            .|..|.|              .| .|:         |::.:                      .|
  Rat   546 HCFKGHC--------------IWLTPD---------ILKRD----------------------GN 565

  Fly   683 WGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSC-----LNFPSRCIGRDRRFVTCNTPQCHK 742
            ||.|:...:|...|           .||::...|.|     .|....|.|....|..||...|
  Rat   566 WGAWTPFGSCSRTC-----------GTGVKFRTRQCDSPHPANGGRTCSGLAYDFQLCNPQDC-- 617

  Fly   743 VPVQTINDFATQVCMQARKSDPEL---TGEGQQ--LP-STLDAS--CKIFCRTRTNG-TKSRRWT 798
              ..::.||..:.|.|.     :|   .|:.|.  || ...||.  |.::|.::..| ..|.:..
  Rat   618 --PNSLADFREEQCRQW-----DLYFEHGDAQHHWLPHEHRDAKERCHLYCESKETGEVVSMKRM 675

  Fly   799 FPDGTTCKAKQHNPEDITYCISGRCERFSCD---NSTSNFFKM-----DSSFCEARSVRPTRDSS 855
            ..|||.|..|    :..:.|:.|.|.:..||   .|.....|.     |::.|:......||...
  Rat   676 VHDGTRCSYK----DAFSLCVRGDCRKVGCDGVIGSRKQEDKCGVCGGDNTHCKVVKGTFTRSPR 736

  Fly   856 DQESRQQTN---RQRYAERQEGKPQKNH--YENEVAKRPSYGQGNHINAPASPYKRRNYHKPYPP 915
            .|:..:...   ..|:...||.....:|  .:|....:....:.||::..:..:........|..
  Rat   737 KQDYIKMFEIPAGARHLLIQETDTTSHHLSVKNLETGKFILNEENHLDPNSRSFIAMGVEWEYRN 801

  Fly   916 EIPR------------------PPPPASASL----------IALDRSSSSESEWVAH-------P 945
            |..|                  |...|..||          :.:|.::..|.:.|.|       .
  Rat   802 EDERETLQTIGPLHGTITVLVIPEGDARISLTYKYMIHEDSLNVDDNNVLEDDSVRHEWALKKWS 866

  Fly   946 GCHSNC-------------MTDSKGV-QGVTSRLTGVESI------QLCSYRI------QPCERL 984
            .|...|             ..|||.| :...|.|...::|      |.||..:      :||
  Rat   867 PCSKPCGGGSQFTKYGCRRRLDSKMVHRAFCSALAKPKAIRRACNPQECSQPVWVTGEWEPC--- 928

  Fly   985 QTAAEYAEQTCARYRQKVRGL------------SGHGAQISASIDEPDRSC---------RVG-- 1026
                   .|:|.|...:||.:            |.|....:....|..|:|         |.|
  Rat   929 -------TQSCGRTGMQVRSVRCIQPLHNNTTRSVHTKHCNDHRPESRRACNRELCPGRWRAGSW 986

  Fly  1027 ---------------------------CQDEFIKYRYYLVNGRNGHFPPGTRCS--PVGKRYCVY 1062
                                       ||:|..:      ..|.....|..|.|  |..|.|.|
  Rat   987 SQCSVTCGNGTQERPVLCRTADDNFGVCQEERPE------TARICRLAPCPRNSSDPSKKSYVV- 1044

  Fly  1063 GRCLEFGDDDLPLDK 1077
             :.|...|.|.|:.|
  Rat  1045 -QWLSRPDPDSPIQK 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848	20/98 (20%)
		ZnMc_ADAMTS_like	331..543	CDD:239801	74/224 (33%)
		Reprolysin	332..545	CDD:279729	75/225 (33%)
		TSP1	683..741	CDD:214559	15/62 (24%)
Adamts2	NP_001382353.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910