Protein Alignment stl and stl

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_061505633.1
• Gene: stl / 1275772
• VectorBaseID: AGAMI1_011954
• Length: 1067
• Species: Anopheles gambiae
• Alignment Length: 1197
• Identity: 475/1197 - (39%)
• Similarity: 656/1197 - (54%)
• Gaps: 218/1197 - (18%)

  Fly     5 AIGSNRHRRLALIVLTTLWLLIGASSSSSSTSSTNP--KSVNIELRRKRSLHYNGIELDKNTLVG 67
            |:||...:.:||:.|    :||.|         .||  :.:::|:.|...|..:..::|:..|..
Mosquito    12 AVGSVMLQIIALLAL----ILIAA---------RNPTVRCLHMEVERVNHLVLDNAKIDERNLHN 63

  Fly    68 HLREHERALIFGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPS 132
            .|.|||:.|:||.|:.:   :||:|::.|                          ::|:.||.|
Mosquito    64 FLEEHEQLLLFGDRTTD---DFKIVNVRQ--------------------------RKRESRSTP- 98

  Fly   133 EDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERCFY 197
              |:|.|   :.....|.:....|:||:|..|||::|.||...:|.||.::.|...:.:...|||
Mosquito    99 --GSGFL---QFNLSDGREDNFALRLQKSDILIDESFAFIESYDNSTQLLDDSYDRVLKYRDCFY 158

  Fly   198 RSPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLYQAR----VDKSGGGYSEASSRR 258
            |:..||.|||| |:|||:.:.|.|::||||||.|||||.||:....    .|:||
Mosquito   159 RNERAAFDLCE-GSVRGLIRTNESEIVIHPLPERFGTGAHVILNRNKTIPSDESG---------- 212

  Fly   259 TASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSR 323
                 ::::.||||   .|||.||               :|......|..|.|.:|:|.....::
Mosquito   213 -----ETKVMFEPD---MNEPTRR---------------RPTVPFYGQSQQSRLKRHISSNHNAK 254

  Fly   324 WSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLK 388
               :|:.|.||||||:|.|||.||.||:|.|||:.::.|:|||||||||||:||:||..|||:||
Mosquito   255 ---VPDVLHIETAIFIDKDLYRHMSKNYPKNTEAHLIRFVLAMINGVQLLYNHPSLGHPINFILK 316

  Fly   389 RLEIWKSWDPPGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDK-GKAN 452
            ||||..: ||..|.||.|::.||||||.||.|:||.|||||:|:|||::||||||....| ||.:
Mosquito   317 RLEILHN-DPKDLRRSSDIDIYLNSFCGWQRKMNPISDADPVHFDHAVILTGLDLFVVSKNGKVS 380

  Fly   453 SQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDPTMHIMSPKLGS 517
            :||||:|.|.||||...||||||.|||||||||:||||||||||||..|.:|||:::||||.|||
Mosquito   381 NQVVGLAPVAGMCTITSSCTINEGKHFESVFVVSHEIGHNLGMRHDTSENNCDPSLYIMSPTLGS 445

  Fly   518 GKVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQA 582
            ||:|||.|||.||..||...||.|||||..:....|||..||||||||:|:|||:|::||:..::
Mosquito   446 GKITWSSCSRNYLNTFLKTSQATCLFDRGHYGSSLDHTGEGRLPGERFDADQQCLLKYGKDSTRS 510

  Fly   583 STQSKMEICRDLHCRQDGLPWTSHPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWPPEHIP 647
            .:|...:|||||||::|...||||||||||.||..||||.|.|.::                 ||
Mosquito   511 KSQDLADICRDLHCQRDRYTWTSHPALEGTNCGKLMWCRSGVCVSK-----------------IP 558

  Fly   648 EATHEKIIRH-------------EPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYG 699
            ..|.:...:|             |..:...|..|.:...|.:|    .|..||||:.|.||||||
Mosquito   559 GLTIQSTGKHITAFKTIDKKTFLEGLKFASLRQDISRTLNTIP----TWDSWSEPTECVSGCLYG 619

  Fly   700 QSRRLLEGSTGLRTLNRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDP 764
            :|.||.|||||||...|.||:....|.|..|::.||...||:.:...||.:|:.|:|.:|::.|.
Mosquito   620 ESGRLKEGSTGLRQFTRKCLDKRKNCSGFSRKYETCIAKQCYNIGRTTILEFSNQICGRAKEFDA 684

  Fly   765 ELTGEG-QQLPSTLDASCKIFCRTRTNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSC 828
            ::.|.| |::....:.|||:||.|:....|::.|.:||||.||.:..:.:|..||:|||||:|||
Mosquito   685 DIIGYGLQKVAEDPEDSCKVFCETKAGVPKTKSWIYPDGTACKVQNGDFDDAYYCVSGRCEKFSC 749

  Fly   829 DNSTSNFFKMDSSFCEARSVRPTRDSSDQESRQQTNRQRYAERQEGKPQKNHYEN--EVAKRPSY 891
            :|:::|::::|.:.|                   |...:|.||   .....|.||  :....|
Mosquito   750 NNTSNNYYRIDGALC-------------------TEVYQYTER---SGNSIHQENVRDYKSLP-- 790

  Fly   892 GQGNHINAPASPYKRR-----------NYHKPYPPEIPRPPPP-------------------ASA 926
                 :|..|.|..||           ||       ..|.|||                   :|:
Mosquito   791 -----LNKNAYPIDRRAESSTIRTALSNY-------TARKPPPDTEGYSSQAENTFNRWRERSSS 843

  Fly   927 SLIALDRSSSSESEWVAHPGCHSNCMTDSKGVQGVTSRLTGVESIQLCSYRIQPCERLQTAAEYA 991
            .|..|......:..|....|||.:||...||||.|:|......:||||:.....|:::.:..|:|
Mosquito   844 ELNRLSELQGRKHNWEVKSGCHFSCMERGKGVQIVSSTAGTNTNIQLCTANTIACDKVLSTYEFA 908

  Fly   992 EQTCARYRQKVRGLSGHGAQISASIDEPDRSCRVGCQDEFIKYRYYLVNGRNGHFPPGTRCS-PV 1055
            .|.|.||:|||.||||.|.||:.||::|||||||.|||.||::|:|||||..||||.||||: ..
Mosquito   909 TQLCKRYQQKVSGLSGIGMQIAPSIEDPDRSCRVACQDTFIRHRFYLVNGEQGHFPFGTRCNHNE 973

  Fly  1056 GKRYCVYGRCLEFGDDDLPLDKTHISLGQLRTRRKRSSISNDL-----FNITEIFIKPSHSDISA 1115
            ..|||:.|:||.||.||:|:::::.:|..:|.:|..:......     .|:||...:....::.|
Mosquito   974 SNRYCINGKCLHFGSDDIPVNESYNALPNVRIKRSTNRTKRHFEYFAPINVTERLSQEFLENLIA 1038

  Fly  1116 ----------------ENIEFTQPIHV 1126
                            |:|:...||:|
Mosquito  1039 NIDFGRTTNENNIVLEEHIDLKNPIYV 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801	142/212 (67%)
		ADAMTS_CR_2	561..625	CDD:465496	38/63 (60%)
		TSP1	683..741	CDD:214559	31/57 (54%)
stl	XP_061505633.1	None