Protein Alignment stl and AdamTS-A

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_061498656.1
• Gene: AdamTS-A / 1274038
• VectorBaseID: AGAMI1_000621
• Length: 1780
• Species: Anopheles gambiae
• Alignment Length: 1113
• Identity: 217/1113 - (19%)
• Similarity: 350/1113 - (31%)
• Gaps: 413/1113 - (37%)

  Fly   171 FIRRTENGTQFVEHSPQLLKR---------LERCFYRSPAAA-------LDLCEPGNVRGVFQQN 219
            ||.:....|.|..:  :.|::         |:.|:|:.....       :.|||  .::|..:..
Mosquito   228 FIHKDMKVTHFFPN--ETLRKPEDHEESRWLQGCYYKGSVVGDAQSNVRVSLCE--GMQGHIKTT 288

  Fly   220 GSDLVIHPLPARFGTGTHVLYQAR---VDKSGGGYSEASSRRTA--SPL----DSQLQFEPDAEE 275
            .:..:|.|......:...:|::.:   .||:..|    :..||.  .|:    |..::.:.:|
Mosquito   289 NASFLIQPADNASNSDARILHRIQRLMTDKTSSG----NDGRTLVDGPITPAQDCAVRTDHEA-- 347

  Fly   276 FNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPE-----ELFIET 335
                     |...|.|      :|..::....|.:|||.             ||     :..:|.
Mosquito   348 ---------ADRSLGS------EPTDNNYFSRHSRRRRS-------------PEHFANNDYTVEV 384

  Fly   336 AIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLG-------RRINFVLKRLEIW 393
            .:.||:.:..:.:.|..|        ::|.:::.|..:|...::|       ..|:::...|:..
Mosquito   385 LVVVDNQMQRYHETNLKT--------YVLTLMSIVSSVYADASIGSSMKIAVTHISYIHHDLDAQ 441

  Fly   394 KSWDPPGL--VRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVV 456
            .:....||  |.:.|:   |..||::::..|       :|:|.||:|| .:.:..:..:.|...:
Mosquito   442 TTAAKKGLEGVSASDM---LQDFCRFKQSTN-------IHHDVALLLT-REQICRNPAENNCDTL 495

  Fly   457 GMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDPTMHIMSPKLGSGKV- 520
            |:|.:..:|... :|.|.:.....:.|.:|||:||.|||.|| .:..|   ........|:.::
Mosquito   496 GLAELGTICRDT-ACAIVQDNGLSASFTIAHELGHVLGMPHD-DDHRC---QRYRGDSSGNNRIM 555

  Fly   521 -----------TWSKCSRTYLEDFLMDPQAECLFDRDSF----AGPWDHTAGGRLPGERFNANQQ 570
                       .||.|||..|.::.......|:.:..|.    :|..|    ..|.||:|..::|
Mosquito   556 SRTIDHNTHPWQWSNCSRQILSEYFEKHPDNCMLNHPSLDLMTSGSMD----SMLAGEKFTNDKQ 616

  Fly   571 CMLRFGK-----NFMQ------ASTQSKMEICRDLHCRQDGLPWTSHPALEGTECGPNMWCRGGT 624
            |.|.||.     ::|.      .|.:::|..|:..|     :||.     :||||....||:.|.
Mosquito   617 CELVFGNGSKICSYMPPCARLWCSWENEMSGCKTQH-----MPWA-----DGTECQEGHWCQKGQ 671

  Fly   625 CEARSSKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPMD-NELPGSPSNWGEWSE 688
            |.                                            |:| ..|......|..||.
Mosquito   672 CV--------------------------------------------PIDRTALKPQNGGWSAWSS 692

  Fly   689 PSACESGCLYGQSRRLLEGSTGLRTLNRSC-----LNFPSRCIGRDRRFVTCNTPQCHKVPVQTI 748
            .:.|...|           ..|::...|.|     .|....|.|....:..|||..|   |....
Mosquito   693 FNECSRTC-----------GGGIQARTRECDSPKPKNGGKFCTGLRIEYRPCNTQPC---PSWRY 743

  Fly   749 NDFATQVCMQARKSDPELTGEGQQLPS-------------TLDASCKIFCRTRTNGTKSRRWTFP 800
            | |..:.|       .|:.|:...:||             .:...||:.||.:   .||..:...
Mosquito   744 N-FREEQC-------HEMDGQNFDVPSLEPNVRWTPKYGTPVADQCKLLCRVQ---DKSLYFMLK 797

  Fly   801 ----DGTTCKAKQHNPED-ITYCISGRCERFSCDNSTSNFFKMDS-SFC--EARSVRPT------ 851
                |||.|..    ||| ...||:|:|.:..||...::..|:|. ..|  :..:.||.
Mosquito   798 EKVIDGTPCTF----PEDSFDMCINGQCRKAGCDYVLNSDAKLDQCGVCRGDNSTCRPVTGRLNL 858

  Fly   852 ------RDSSD--QESR---------------------------------------QQTNRQR-- 867
                  |.|||  .|.|                                       ..|:|.|
Mosquito   859 GKGVVRRVSSDGPMEFRIPEGATSINIINTGYMKDACYLSVMSGNEIIFNDPKHLTPHTSRHRLF 923

  Fly   868 --------YAERQE------GKP----------QKNHYE-------------------------- 882
                    ....:|      |:|          .|.|.|
Mosquito   924 AGVRLEYTVTSSEERITSTFGRPLKEKLTVRVIHKKHVELHKGFVDYSYMVPVHPFGNTLSNAIY 988

  Fly   883 NEVAKRPSYGQGNHINAPASPYKRRNYHKPYPPEIPRPPPPASASLIALDRSSSSESEWVAHPGC 947
            ::|...| |...:|.:  .|.|...:.|:..|...|.|..|....|          :.|..   |
Mosquito   989 SKVEPDP-YDHPHHTH--HSHYSGNSVHRLQPTVAPTPESPYRWEL----------APWTE---C 1037

  Fly   948 HSNC---------MTDSKGVQGVTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCARYRQKVR 1003
            ...|         ..|::..|.|        |...|:..::|    |...|.....|..|.
Mosquito  1038 DQQCTGKKRRTAICVDAEAQQQV--------SPDYCNQSVKP----QDEFESCNTECHFYW---- 1086

  Fly  1004 GLSGHGAQISASIDEPDRS-CRVGCQD-----EFIKYRYYLVNGRNGHFPPGTRC----SPVGKR 1058
                          ||.|: |...|.:     |:...|.|....|..|. ....|    .||..|
Mosquito  1087 --------------EPGRTECSSACGEGTKKIEYKCVRSYSQTQRKEHV-DDAMCYGSTKPVNIR 1136

  Fly  1059 YCVYGRCL 1066
            ....|.|:
Mosquito  1137 ETCMGPCM 1144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801	51/232 (22%)
		ADAMTS_CR_2	561..625	CDD:465496	22/74 (30%)
		TSP1	683..741	CDD:214559	14/62 (23%)
AdamTS-A	XP_061498656.1	None