Protein Alignment stl and WFIKKN2

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_783165.1
• Gene: WFIKKN2 / 124857
• HGNCID: 30916
• Length: 576
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 94/529 - (17%)
• Similarity: 156/529 - (29%)
• Gaps: 207/529 - (39%)

  Fly   662 IPPLLHDYNPM-DNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLNFPSRC 725
            :||:.:.:..: .|::  :|:.|.:      .:|.|     ||..|......|..:.|   |:.|
Human    35 LPPIRYSHAGICPNDM--NPNLWVD------AQSTC-----RRECETDQECETYEKCC---PNVC 83

  Fly   726 IGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELTGEGQQLPSTLDASCKIF-CRTRT 789
                                      .|:.|:.||..|  :.|:...:....:|:|..| |..:
Human    84 --------------------------GTKSCVAARYMD--VKGKKGPVGMPKEATCDHFMCLQQ- 119

  Fly   790 NGTKSRRWTFPDG-TTCKAKQHNPEDITYCISGRCER---FSCDNSTSNFFK---MDSSFCE--- 844
             |::...|   || ..||.|.            |||:   |:|.:....::.   ||:..|.
Human   120 -GSECDIW---DGQPVCKCKD------------RCEKEPSFTCASDGLTYYNRCYMDAEACSKGI 168

  Fly   845 ---------------------ARSVRPTRDSSD----------------QESRQQTNRQRYAERQ 872
                                 ..::.||..|.:                .:|........:....
Human   169 TLAVVTCRYHFTWPNTSPPPPETTMHPTTASPETPELDMAAPALLNNPVHQSVTMGETVSFLCDV 233

  Fly   873 EGKP--------QKNHYENEVAKRPSYGQGNHI----------NA---PASPY--KRRN----YH 910
            .|:|        |....|| |..||::.:||.:          ||   .|..|  ..||    ..
Human   234 VGRPRPEITWEKQLEDREN-VVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARNVAGVLR 297

  Fly   911 KPYPPEIPRPPPPASASLIALDRSSSSESEWVAHPGCH---------------SNCMTDSKGVQG 960
            ..:|..:.|....|:.|..:.:.::...:|.:..|...               :||:|.:.|  .
Human   298 ADFPLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFG--H 360

  Fly   961 VTSRLTGVESIQLCSYRIQ--------------PCERLQTAAEYAEQT--CARYRQKVRGLSGHG 1009
            ....|...|:.:.|.....              ||:.......|..||  |..:  ...|..|:|
Human   361 CHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSF--VYGGCEGNG 423

  Fly  1010 AQISASIDEPDRSCRVGCQDEFIKYRYYLVNGRNGHFPPGTR----CSPVGK---RYC-----VY 1062
            ...     |...:|...|.                 ||.|.:    |.|..|   .:|     :.
Human   424 NNF-----ESREACEESCP-----------------FPRGNQRCRACKPRQKLVTSFCRSDFVIL 466

  Fly  1063 GRCLEFGDD 1071
            ||..|..::
Human   467 GRVSELTEE 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848
		ZnMc_ADAMTS_like	331..543	CDD:239801
		Reprolysin	332..545	CDD:279729
		TSP1	683..741	CDD:214559	10/57 (18%)
WFIKKN2	NP_783165.1	WAP	44..90	CDD:278522	14/87 (16%)
		KAZAL_FS	138..174	CDD:238052	7/35 (20%)
		I-set	216..304	CDD:254352	18/88 (20%)
		Ig_3	224..304	CDD:143242	17/80 (21%)
		Kunitz_BPTI	328..379	CDD:278443	8/52 (15%)
		Kunitz_BPTI	385..436	CDD:278443	11/57 (19%)
		NTR_WFIKKN	455..563	CDD:239630	4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900