Protein Alignment stl and adamts3

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_073805801.1
• Gene: adamts3 / 102467218
• ZFINID: ZDB-GENE-110223-1
• Length: 1211
• Species: Danio rerio
• Alignment Length: 885
• Identity: 222/885 - (25%)
• Similarity: 337/885 - (38%)
• Gaps: 237/885 - (26%)

  Fly    93 HLAQQRPEEQQRLEER-KRPG-------EAEQH------GGNPHQRRQRRSLPSEDGNGPLPPEE 143
            |||.:..:::..|:.| |..|       :||.|      ..|..||.:|..|   :|:.|.|...
Zfish    21 HLAGEIIDKEDLLKNRLKEYGLITPISTDAEGHFLSHFLSANHKQRVKRDVL---EGSAPAPDRL 82

  Fly   144 EEQEAGEDVEARLQLQQSPQLI---------DDAFIFIRRTENGTQFVEHSPQLLKR---LERCF 196
            .........|..|:|..:.:|:         ||..|....|:|.|    |..::|||   ...|.
Zfish    83 FFNITVFGKEFHLRLHPNQRLVAPGAMVEWHDDIEIAGNATDNRT----HFERILKRELLKTDCT 143

  Fly   197 YRS-----PAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGT-------GTHVLYQARVDKSGG 249
            :..     |.|::.:.....:.|:.:.:..:..|.||..  ||       ..||:|
Zfish   144 FIGDITDVPGASVAINNCDGLAGMIRTDSDEYFIEPLEQ--GTQEHEERGRVHVVY--------- 197

  Fly   250 GYSEASSRRTA---SPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQR 311
                   ||:|   :|.|..|.::|...|.:.||.......|:...:                 |
Zfish   198 -------RRSAVLQTPSDISLDYQPIEPELDTPRMLDNIAKQVNKTV-----------------R 238

  Fly   312 RRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHH 376
            |||:.||          |:..||..:.||..:.....|       ..|.::||.::|.|..:||.
Zfish   239 RRRHAGD----------EDYNIEILLGVDDSVVRFHGK-------EHVQNYLLTLMNIVNEIYHD 286

  Fly   377 PTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKW---QEKLNPFSDADPLHYDHALVL 438
            .:|...||.||.|:.:........|:...:....|.:.|:|   |:|.:|....   |:|||:.|
Zfish   287 ESLEVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAFVQQKEDPEHSE---HHDHAIFL 348

  Fly   439 TGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEIS 503
            |       .:|...:.:.|.|.|.|||..:.|||:|....|.|.||||||.||.|||.||.:...
Zfish   349 T-------RQGFGPTGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNR 406

  Fly   504 C-DPTM--HIMSPKLGSG--KVTWSKCS----RTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGR 559
            | |.|.  .:|:|.:.:.  :..||.||    :.|:..:      :||.| |.|...|....  .
Zfish   407 CGDETAMGSVMAPLVQAAFHRYHWSMCSGQELKRYIHSY------DCLLD-DPFKHDWPQLP--E 462

  Fly   560 LPGERFNANQQCMLRFGKNFMQASTQSKMEICRDLHCRQDGLPW----TSHPALEGTECGPNMWC 620
            |||..::.::||...||..:...::....:.|:.|.|.....|:    ...|.|:||||.|..||
Zfish   463 LPGINYSMDEQCRFDFGVGYKICTSFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWC 527

  Fly   621 RGGTCEARSSKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGE 685
            ..|.|..:::.|                      ::.:                      ..||.
Zfish   528 YKGHCMWKNANQ----------------------VKQD----------------------GAWGA 548

  Fly   686 WSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLN-FPSR----CIGRDRRFVTCNTPQCHKVPV 745
            ||:..:|...|           ..|:|...|.|.| .||.    |.|.:..:..|||..|.|
Zfish   549 WSKYGSCSRSC-----------GMGVRFRTRQCNNPVPSNGGQDCPGVNYEYQLCNTDDCPK--- 599

  Fly   746 QTINDFATQVCMQARKSDPEL-TGEGQQLP-STLDAS--CKIFCRTRTNGTKS-RRWTFPDGTTC 805
             ...||..|.| |.|.|..|. ..:...|| ...||:  |.::|:::..|..: .:....|||.|
Zfish   600 -HFEDFRAQQC-QLRNSHFEYQNAKHHWLPYEHPDANKRCHLYCQSKETGDVAYMKQLVHDGTRC 662

  Fly   806 KAKQHNPEDITYCISGRCERFSCDNST-SNFFKM---------DSSFCEARSVRPTRDSSDQESR 860
            ..|  :|..|  |:.|.|.:..||... ||  |:         |:|.|  |:|:.|.....:::.
Zfish   663 SYK--DPYSI--CVRGECVKVGCDREIGSN--KVEDKCGVCGGDNSHC--RTVKGTFTRVPKKAG 719

  Fly   861 QQTNRQRYAE---------RQEG-----KPQKNHYENEVA 886
            ::..::...|         :..|     |..:|.|.||.|
Zfish   720 KKLTKRSQKEIHVLENTIWKTRGAFLLPKGARNVYLNETA 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801	68/223 (30%)
		ADAMTS_CR_2	561..625	CDD:465496	20/67 (30%)
		TSP1	683..741	CDD:214559	18/62 (29%)
adamts3	XP_073805801.1	None