Protein Alignment stl and adamts17

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_073764157.1
• Gene: adamts17 / 101884120
• ZFINID: ZDB-GENE-121030-7
• Length: 1134
• Species: Danio rerio
• Alignment Length: 1106
• Identity: 255/1106 - (23%)
• Similarity: 392/1106 - (35%)
• Gaps: 316/1106 - (28%)

  Fly    99 PEEQQRLEERKRPGEAEQH---GGNPHQR-RQRRSLPSEDGNGPLPPEEEEQ------EAGEDVE 153
            |:|.|       ||  |.|   |||...| |:|||          .|::|:.      ..|:  |
Zfish    37 PQELQ-------PG--EMHLLSGGNRWSRGRKRRS----------DPQQEDHLFLRLPAFGK--E 80

  Fly   154 ARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERCFYRSPA-------AALDLCEPGN 211
            ..|:||:....:.:.|:...|.|.|:  |:|  :.|.::.||||....       .:||.|  |.
Zfish    81 LYLELQRDASFLTEGFVTEERREEGS--VQH--ESLPKVRRCFYTGAILNHTDSFVSLDTC--GG 139

  Fly   212 VRGVFQQNGSDLVIHPLPARFGTGTHVLYQARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEF 276
            :.|:.|.....|.|.|:             .:...|..|:.....|...|..|.........|:|
Zfish   140 LTGLVQTAEERLFIEPV-------------GQAADSFSGWEHRVIREKHSSPDGPAPAADGREQF 191

  Fly   277 NEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFVDS 341
                    .||       :..:.:...|....|.|.||   :|.|     :..|..:||.:..|:
Zfish   192 --------CQS-------IHDKKKEKRPRGAEQVRGRR---NAIR-----LSREYTVETLVVADA 233

  Fly   342 DLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRD 406
            ::..:       :.......|||.::|.|..::.|.:||.|:|..:.:|.:..: .|..|.....
Zfish   234 NMVQY-------HGAEAAQRFLLTVMNMVYNMFQHQSLGLRLNIRVTKLVLLHN-RPEKLKVGHH 290

  Fly   407 VENYLNSFCKWQEKLN----------PFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATV 461
            .|..|.|||.||.:..          |.|..||...|.|:::|..|...:.....::  ||:|.:
Zfish   291 GEKALESFCHWQHEEYGARYLGNNHVPGSRDDPPPVDAAVLVTRTDFCVHKDEPCDT--VGIAYL 353

  Fly   462 KGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDPTMHIMSPKLGSGK----VTW 522
            .|.|:|...|.:.|.......|.:|||:|||:||.||....||....||||.:...|:    ::|
Zfish   354 GGTCSSKRKCVLAEDNGLNLAFTIAHELGHNMGMSHDDDHASCTGHSHIMSGEWVKGRNPSDLSW 418

  Fly   523 SKCSRTYLEDFLMDPQAECLFDRDSFAGPWDH---TAGGRLPGERFNANQQCMLRFGKNFMQAST 584
            |.|||..||.||....:.||...|    |.:.   ....:|||..::|::||.:.||.|   |:.
Zfish   419 STCSRDDLEKFLRSKASGCLLHTD----PRNRYLVRLPAKLPGMHYSADEQCQILFGTN---ATF 476

  Fly   585 QSKME--ICRDLHCRQDGLPWTS-----HPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWP 642
            .:.||  :|..|.|..:|  .||     .|.|:|||||.:.|||.|.|.:::            |
Zfish   477 CTDMEHLMCAGLWCLVEG--DTSCKTKLDPPLDGTECGADKWCRAGECVSKT------------P 527

  Fly   643 -PEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLE 706
             |:|:                                 ..:|..||..|.|...|
Zfish   528 IPQHV---------------------------------DGDWSPWSTWSMCSRTC---------- 549

  Fly   707 GSTGLRTLNRSCLNFP-----SRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPEL 766
             .||.|...|.|.|.|     ..|.........|..|.|.| .:.|..|      .|.:..:.:.
Zfish   550 -GTGARFRQRKCDNPPPGPGGKYCQKASVEHKVCEGPPCTK-GLPTFRD------QQCQSHERQA 606

  Fly   767 TGEGQQLPSTLD--ASCKIFCRTRTNGTKSRRWTFP--------DGTTCKAKQHNPEDITYCISG 821
            :.:.|...:.:|  ..|.::|  ...|:.|     |        |||.|     .|.:...|::|
Zfish   607 SKKSQMWTAVIDDEKPCALYC--TPVGSDS-----PVLVAERVLDGTPC-----GPYESDLCVNG 659

  Fly   822 RCERFSCDNSTSNFFKMD-SSFC--EARSVRPTRDSSDQE------------SRQQTNRQR---- 867
            :|::..||....:..|.| ...|  :.:|.|..:...:..            |....::.|
Zfish   660 KCQKIGCDGIIGSSAKEDRCGVCNGDGKSCRIIKGDFNHSKGMVPHSLCKKVSTCVMSKPRAVLK 724

  Fly   868 ----YAERQ------------EGKPQKNHYENEVAKRPSYGQGNHINAPAS--------PYKRRN 908
                |.|..            |.||..:....:.:.:.|......|..|..        .|.||.
Zfish   725 CFSCYIEAAVIPVGARRIKVVEDKPSHSFLALKDSSKRSINNDWKIELPGEFELAGTTVRYVRRG 789

  Fly   909 YHKPYPPEIPRPPPPASASL--------------IALDRSSSSESEWVAHP------------GC 947
            ..:....:.|...|.....|              :||:.|..:.|:.|..|            .|
Zfish   790 LWEKMSAKGPTKTPLHLMVLLFHDQTYGIHYEYTVALNHSQENSSDLVKEPEHMYLWTHSSWEDC 854

  Fly   948 HSNCMTDSKGVQGVTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCARYRQ------KVRGLS 1006
            ..:|        |...|.|.|..:::.:..:.|..  .::.:...:...:.||      :.|.::
Zfish   855 SVHC--------GGGERRTVVSCMRIINKTMTPVN--DSSCQVENKPSPQIRQCNIHPCQYRWVT 909

  Fly  1007 GHGAQISASIDEPDRSCRVGCQDEFIKYRYYLVNGRNGHFPPGTR---C---SPVGKRYCVYGRC 1065
            |...|.|.       :|..|.|...:...|.|   :||.:.| ||   |   .|...::|....|
Zfish   910 GDWTQCSL-------TCGKGLQQREVGCIYQL---QNGTYIP-TRDLYCLSSKPASVQHCEGRHC 963

  Fly  1066 L 1066
            |
Zfish   964 L 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801	67/225 (30%)
		ADAMTS_CR_2	561..625	CDD:465496	28/70 (40%)
		TSP1	683..741	CDD:214559	16/62 (26%)
adamts17	XP_073764157.1	None