Protein Alignment stl and adamts16

DIOPT Version :9

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_031760055.1
• Gene: adamts16 / 100498052
• XenbaseID: XB-GENE-986244
• Length: 1234
• Species: Xenopus tropicalis
• Alignment Length: 1299
• Identity: 287/1299 - (22%)
• Similarity: 436/1299 - (33%)
• Gaps: 475/1299 - (36%)

  Fly   122 HQRRQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTENGTQFVE-HS 185
            |:.|::||..:.|.:.   ...:....|:|:  .|:|:.:.:|:...|......|..|:.:: .|
 Frog    80 HKHRKKRSAANVDNDA---VHLKLHGFGQDL--HLELKVTERLLAPGFKIQTFGEGRTKSIKTFS 139

  Fly   186 PQLLKRLERCFYR-------SPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARF----------G 233
            .|     :.|||:       :.:.||..|  ..:.|:.:...::..:.|:|...          |
 Frog   140 SQ-----DFCFYQGSVVSHENSSVALSTC--SGLSGLIRTQEAEYFLKPMPRHVALKHNYSSSDG 197

  Fly   234 TGTHVLYQARVDKSGGGYSEASSRRTASPLDSQ-------LQFEPDAEEFNEPRRRLRAQSQLQS 291
            :..||||:..:||.....::.::.:|...|.:|       :......:|.|:...||.
 Frog   198 SQHHVLYKRSLDKLLYKNNDINTVQTQQELINQKWQHLDTVSHHDSHQEMNQKYERLE------- 255

  Fly   292 PLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEE-------------------LFIETAI 337
                         .||:..||::||...|:......|:|                   |.:||.:
 Frog   256 -------------KQHYCGRRKKYIPKPPKKDMYIFPDEYRYQGRFKRSLIKLSKSKQLNVETLV 307

  Fly   338 FVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLV 402
            .||..:   ||.:...|    :.:::|.::|.|..|:...::|..||..:..|.:.:. |.|||:
 Frog   308 VVDKKM---MQNHGHEN----ITTYVLTILNMVSALFKDGSIGGNINIAIVGLILLED-DQPGLI 364

  Fly   403 RSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTS 467
            .:...::.|:|||.||..|   ...|...:|||::|||||:.::.....::  :|.|.:.|||:.
 Frog   365 INHHADHTLSSFCHWQSGL---VGKDGSRHDHAILLTGLDICSWKNEPCDT--LGFAPISGMCSK 424

  Fly   468 IYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDPTM-HIMSPKLG--SGKVTWSKCSRTY 529
            ..|||:||.......|.:|||.|||.||.||.:...|..:. :||||.|.  :|..:||.|||.|
 Frog   425 YRSCTVNEDTGLGLAFTIAHESGHNFGMVHDGEGNMCKKSEGNIMSPTLAGHNGVFSWSFCSRQY 489

  Fly   530 LEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQSKMEICRDL 594
            |..||...||.||.| |...|. ::....:|||..::||.||..:||:.........|.:||:.|
 Frog   490 LYKFLSSAQAVCLAD-DPKPGK-EYKYPEKLPGVLYDANIQCKWQFGEKAKLCMLDFKKDICKAL 552

  Fly   595 HCRQDGLPWTSH--PALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWPPEHIPEATHEKIIRH 657
            .|.:.|....:.  ||.|||.||.:||||.|.|.       :|.       |..|:||
 Frog   553 WCHRVGRKCETKFMPAAEGTICGHDMWCRRGQCV-------NYG-------EEGPKAT------- 596

  Fly   658 EPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLN-F 721
                                  ...|.|||..|.|...|..|.|.:           .|.|.| .
 Frog   597 ----------------------DGQWSEWSTWSPCSRTCGGGVSYK-----------ERQCTNPR 628

  Fly   722 PSR----CIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKS---------DPELTGEGQQL 773
            ||.    |.|..|....||...|.|..:    ||..|.|.:....         .|....|..:.
 Frog   629 PSHGGKFCEGSSRVNKLCNNQSCPKNNI----DFRAQQCAEYNSKPFRGWYYNWKPYTRVEEHEY 689

  Fly   774 PSTLDASCKIFCRTR--------TNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSCD- 829
                   ||::|...        :|..|       |||||....:|     .||.|.||...||
 Frog   690 -------CKLYCIAEGFDFFFSLSNKVK-------DGTTCSEYSNN-----VCIDGICETVGCDH 735

  Fly   830 ----NSTSNF---FKMDSSFCE------------------------ARSVRPTR-DSSDQESRQQ 862
                |:..:.   .|.|:|.|:                        |||:|... :.|......:
 Frog   736 LLGSNAVQDICGVCKGDNSTCKVYRSHYTKQHYSNQYYSIVTIPAGARSIRINEMNISTSYISIR 800

  Fly   863 TNRQRY----------------------AERQEGKPQ--------------------KN---HYE 882
            .|.::|                      .:|....|:                    ||   .:|
 Frog   801 NNEKKYYLNGHWTVDWPGQYKFAGSVFHYKRPFNNPESLSTAGPINETLVVEIFLQGKNPGIAWE 865

  Fly   883 NEVAKRPSYGQ---------------------GNHINAPASPY--------------KRRNYHKP 912
            ..:||..|..:                     |.|:|.....|              |.|....|
 Frog   866 YSMAKSVSVKKPTIKHNYTWAIIKSECSVSCGGGHMNTKEGCYKDMRVQVNTSFCSAKNRPVTGP 930

  Fly   913 YP----PEIPR-------------------------------------------PP--------- 921
            .|    |.:||                                           ||
 Frog   931 LPCNPQPCLPRWSVGNWTECSQTCGSGEQFRQVQCKQRKHFKLEIVANKLCTMPPPLHRQICNTQ 995

  Fly   922 --PPASASLIALDRSSSSESEW--------VAHPGCHSN------CMTDSKGVQG---VTSRLTG 967
              |||.:.....:.|.:....|        ..:|..|:.      |.|:.|.|..   :..|...
 Frog   996 SCPPAWSVGTWSECSRTCGKGWRKRTVVCKSTNPSLHAQVLPDGACTTEFKPVIQEICIVKRCNK 1060

  Fly   968 VESIQL-------CS--------YRIQPCERLQTAAEYAEQTCARYRQKVRGLSGHGAQISASID 1017
            .:.:|.       ||        .||..|.....:.:|.|               .|.:..:.:.
 Frog  1061 PKKLQWIISNWSECSTTCGSGSQRRILRCIEKYVSGKYRE---------------FGPKKCSHLQ 1110

  Fly  1018 EP----DRSCRVGCQDEFIKYRYY-LVNGRNGHF---------------------------PPGT 1050
            :|    :|:|   .|.|.:||||| :||.:.|.:                           .|.|
 Frog  1111 KPNMELERTC---LQAECLKYRYYSVVNQQRGSWYSSEWSQCTVSCGGGMQVRIVQCLSNGKPAT 1172

  Fly  1051 RCSPVGK----RYCVYGRCLEFGDDDLPLDKTHISLGQLRTRRKRSSISNDLFNITEIFIKPSH 1110
            ||.|..|    :.|        ..|..|.:             |:.::..|.||  ..::.|.|
 Frog  1173 RCQPHQKPKSSQAC--------NTDFCPSE-------------KKDNLCKDYFN--WCYLVPQH 1213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	Pep_M12B_propep	<155..239	CDD:279848	19/101 (19%)
		ZnMc_ADAMTS_like	331..543	CDD:239801	76/214 (36%)
		Reprolysin	332..545	CDD:279729	76/215 (35%)
		TSP1	683..741	CDD:214559	19/62 (31%)
adamts16	XP_031760055.1	TSP1	600..652	CDD:214559	19/62 (31%)
		ADAM_spacer1	757..868	CDD:368694	12/110 (11%)
		TSP1_ADAMTS	942..997	CDD:408800	2/54 (4%)
		TSP1_ADAMTS	1001..1058	CDD:408800	8/56 (14%)
		TSP1_ADAMTS	1066..1125	CDD:408800	12/76 (16%)
		TSP1_ADAMTS	1141..1191	CDD:408800	8/57 (14%)
		PLAC	1200..1230	CDD:400844	5/16 (31%)
		Pep_M12B_propep	80..204	CDD:396235	27/135 (20%)
		ZnMc_ADAMTS_like	301..502	CDD:239801	75/213 (35%)
		ADAM_CR_2	519..586	CDD:407643	26/66 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13723
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010