Protein Alignment stl and adamts9

DIOPT Version :10

• Sequence 1: NP_001097423.1
• Gene: stl / 37619
• FlyBaseID: FBgn0086408
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_001410599.1
• Gene: adamts9 / 100333407
• ZFINID: ZDB-GENE-070814-6
• Length: 1443
• Species: Danio rerio
• Alignment Length: 1189
• Identity: 263/1189 - (22%)
• Similarity: 415/1189 - (34%)
• Gaps: 383/1189 - (32%)

  Fly    67 GHLREHERALI--FGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKR---PGEA--EQHGGNPHQR 124
            |.||..|:|.:  ||:.  |.....:|..:.:|.| .....:.|||   |..|  ..|..:||..
Zfish    25 GRLRGSEKAKLQEFGAY--EIVTPARLNEVGEQLP-TGVHFKRRKRSTDPTTANISHHWTSPHAY 86

  Fly   125 RQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFI-------FIRRTENGTQFV 182
            .|..:.                  |:|....|.|       :..||       .:..:..|...|
Zfish    87 YQISAF------------------GQDYYLNLTL-------ESGFIAPVYTVTILGASSEGHNSV 126

  Fly   183 EHSPQLLKRLERCFYR-------SPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLY 240
            |...:.....:.|||:       ...|.:.||  ..:.|.|:....:..:.||.:.  ...|  |
Zfish   127 EGEEEEDTEYQHCFYKGHVNAGQEHTAVISLC--SGLLGTFRSPEGEFFVEPLHSY--NSEH--Y 185

  Fly   241 QARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSP---------LRLR 296
            :....|....|.:.:|::|   :|.....|....  .||.||.|.:.:.:||         |..|
Zfish   186 EEEHIKPHVVYRKDASKKT---VDDSAACETSGH--TEPNRRHRNRLKRKSPSSMLSDLETLNSR 245

  Fly   297 FQP----RHH--------HPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQK 349
            ..|    :|:        .||    :|.:|:: ..||          |:|..:..||.:..|...
Zfish   246 LFPFSENKHNSANESSDSKPH----RRSKRFL-SYPR----------FVEVMVVADSKMVEHHGS 295

  Fly   350 NFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKS-WDPPGLVRSRDVENYLNS 413
            |        :..::|.:::.|..:|..|::|..||.|:.:|.|.|: .|.|.:  |.:.:..|.:
Zfish   296 N--------LQHYILTLMSIVSSIYKDPSIGNLINIVIVKLVIIKNELDGPTI--SFNAQATLKN 350

  Fly   414 FCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKH 478
            ||.||:..|...|..|.|:|.|:::|..|:.   :.:.....:|:|.:..:|....||:|||...
Zfish   351 FCIWQQSQNHPDDNHPSHHDTAILITRQDIC---RARDKCDTLGLAELGTVCDPYRSCSINEDNG 412

  Fly   479 FESVFVVAHEIGHNLGMRHD----AKEISCDPTMHIMSPKLG--SGKVTWSKCSRTYLEDFLMDP 537
            ..:.|.:|||:||...|.||    .||.......|:|:|.|.  :....||||||.|:.:||...
Zfish   413 LSTAFTIAHELGHVFNMPHDDSNKCKEDGVKNQQHVMAPTLNYYTNPWMWSKCSRKYITEFLDTG 477

  Fly   538 QAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQ--SKMEICRDL------ 594
            ..|||.| :..:.|  ::...:|||:.::.|:||.|.||     ..||  ..|..||.|
Zfish   478 YGECLLD-EPVSRP--YSLSQQLPGQIYSVNKQCELIFG-----PGTQVCPYMTQCRRLWCTSPD 534

  Fly   595 ----HCRQDGLPWTSHPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWPPEHIPEATHEKII 655
                .||...:||.     :||:|.|...|:.|.|                        .|::
Zfish   535 GVQRGCRTQHMPWA-----DGTDCAPGKHCKHGLC------------------------IHKE-- 568

  Fly   656 RHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLN 720
                       |:|.|::..       ||.||....|...|           ..|::...|.| |
Zfish   569 -----------HEYVPVEGA-------WGVWSPFGTCSRTC-----------GGGIKIAVREC-N 603

  Fly   721 FP------SRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELTGEGQQLPST--- 776
            .|      ..|:||..:|.:||:..|.|..    .||..:.|.........:.|    ||..
Zfish   604 RPVPRNGGKYCVGRRMKFRSCNSEPCSKQK----KDFREEQCASFDGRHFNING----LPPNVRW 660

  Fly   777 --------LDASCKIFCRTR-TNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSCD--- 829
                    :...||:|||.. :......|....|||.|     .|:....|:.|.|.:..||
Zfish   661 VPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVTDGTQC-----GPDTNDICVQGLCRQAGCDHVL 720

  Fly   830 NSTSNFFKM-----DSSFCEARS-------------VRPTRDSSDQESRQQTNRQRYAERQEGKP 876
            ||.:...|.     |:|.|:..:             ||....:::.:.||.:        ..||.
Zfish   721 NSKARRDKCGVCGGDNSSCKPVAGTFNIVHYGYNVVVRIPSGATNIDVRQHS--------YSGKA 777

  Fly   877 QKNHYENEVAKRPSYGQ----GNHINAPASPYKRR------------------------------ 907
            :.::|   :|...|.|:    |:.:   .|.:||.
Zfish   778 EDDNY---LALSNSRGEYLLNGDFV---VSMFKREVRVGNAVIEYSGSDHVVERINCTDRIEEEI 836

  Fly   908 --------NYHKP---YPPEIP---RPP--------PPASASLIALDR-------SSSSESEWVA 943
                    |.:.|   |...||   :|.        |....||:....       :..|:...|:
Zfish   837 IIQVLSVGNLYNPDVRYSYNIPIEDKPQHFFWDAYGPWQDCSLLCQGERKKKILCNRESDRVVVS 901

  Fly   944 HPGCH---------SNCMTDSK-----------------GVQGV------TSRLTG-VESI--QL 973
            ...||         .:|.||.:                 |.:.:      .|||.| .:.:  :.
Zfish   902 DQRCHGLPKPAAITESCNTDCELGWHIARKSECTAACGVGYRSLDIYCTKQSRLDGKTQKVDERY 966

  Fly   974 CSYRIQPCERLQTAAEYAEQTCARYRQKVRGLSGHGAQISASIDEPDRSCRVGCQDEFIKYRYYL 1038
            ||.:.:|.::         :.|       .|....|....:|..|..|||..|.:      |...
Zfish   967 CSSQHKPNDK---------EVC-------HGDCNPGGWEYSSWSECSRSCGGGTR------RRNA 1009

  Fly  1039 VNGRNGHFPPGTRCSPVGK 1057
            :.|::......::|:|..|
Zfish  1010 ICGKSDERDDDSKCNPQEK 1028

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stl	NP_001097423.1	ZnMc_ADAMTS_like	331..543	CDD:239801	67/218 (31%)
		ADAMTS_CR_2	561..625	CDD:465496	24/75 (32%)
		TSP1	683..741	CDD:214559	17/63 (27%)
adamts9	NP_001410599.1	Pep_M12B_propep	42..196	CDD:460254	35/185 (19%)
		ZnMc_ADAMTS_like	277..483	CDD:239801	68/228 (30%)
		ADAMTS_CR_2	498..565	CDD:465496	25/100 (25%)
		TSP1	578..630	CDD:214559	17/63 (27%)
		ADAMTS_CR_3	635..739	CDD:437068	27/112 (24%)
		ADAMTS_spacer1	741..858	CDD:461796	17/130 (13%)
		TSP1_ADAMTS	868..919	CDD:465950	7/50 (14%)
		TSP1_ADAMTS	926..979	CDD:465950	8/61 (13%)
		TSP1_ADAMTS	988..1039	CDD:465950	11/47 (23%)
		TSP1_ADAMTS	1042..1093	CDD:465950
		TSP1_ADAMTS	1096..1150	CDD:465950
		TSP1_ADAMTS	1172..1225	CDD:465950
		TSP1_ADAMTS	1228..1281	CDD:465950
		TSP1_ADAMTS	1320..1371	CDD:465950
		TSP1_ADAMTS	1374..1427	CDD:465950