DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB and CYCB2;4

DIOPT Version :9

Sequence 1:	NP_726244.1	Gene:	CycB / 37618	FlyBaseID:	FBgn0000405	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001323249.1	Gene:	CYCB2;4 / 843964	AraportID:	AT1G76310	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	497	Identity:	139/497 - (27%)
Similarity:	222/497 - (44%)	Gaps:	102/497 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 LGSTNGNGNGAV-PPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKVTVKSSSSENVNEPTLKRED 150
            :|.::.|.:|.: |....:||    ||...|   :||                   |..| :|..
plant     1 MGGSDENRHGVIGPMNRQQGG----LRGGKV---IPT-------------------NGQT-RRAL 38

  Fly   151 SNLSKKSL--TKLRAALAKPVMGVSGI---RREPVAVSRKEAETKKELPETKKDSLEVKKDATRM 210
            ||::|..:  .....|:.:|....:||   :..||.|.|  ..|:|...:..:::|::.|:.|:.
plant    39 SNINKNIIGAPVYPCAVKRPFTEKNGICNKKIPPVPVHR--PVTRKFAAQLAENNLQIHKEETKK 101

  Fly   211 PLIRGNSAVTTTTSTM-------------PTTMSLSSKRLAGIE----------------DIDAN 246
            |.:..|.|:....:.:             ...|.....::.|||                |||:.
plant   102 PDLISNEALDRIITDVEEGDFNEPMFVQHTEAMLEEIDKMEGIEMQDSNDIDAEVEESVMDIDSC 166

  Fly   247 DKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETF 311
            ||.|.:.|.||:||||.:..:.|....:..:::..|.:::.:||.:|.||:.|||.:|.|..||.
plant   167 DKNNPLSVVEYINDIYCFYKKNECRSCVPPNYMENQHDINERMRGILFDWLIEVHYKFELMEETL 231

  Fly   312 QLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQM-- 374
            .|.:.:|||:|.|.:...|..||||||||:.:|.||||:..|.:.|.:.|:|..||..:|..|
plant   232 YLTINLIDRFLAVHQHIARKKLQLVGVTAMLLACKYEEVSVPVVDDLILISDKAYTRTEILDMVK 296

  Fly   375 --------------------------ELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSK 413
                                      |..:...:..|...|.|..|:||:.|||.::.:...:|.
plant   297 SFTKSCPDYNHGCSALYVDDHYCVLQEKLMANTLQFNFCLPTPYVFMRRFLKAAQSDKKLELLSF 361

  Fly   414 YFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPI 478
            :.|||..|:|||..|.||::||::::.:...|.       |:.|  |:.|..|:|.|:...|...
plant   362 FMIELCLVEYEMLQYTPSQLAASAIYTAQSTLK-------GYED--WSKTSEFHSGYTEEALLEC 417

  Fly   479 TRLIAKLARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALM 520
            :|.:..|...|...||..::.||..||| ..|.|.|..|.|:
plant   418 SRKMVGLHHKAGTGKLTGVHRKYNTSKF-GYAARIEPAGFLL 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	Cyclin_N	260..387	CDD:278560	47/154 (31%)
CycB	NP_726244.1	Cyclin_C	389..515	CDD:281044	42/125 (34%)
CYCB2;4	NP_001323249.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I3347
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	193	1.000	Inparanoid score	I1359
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	1	1.000	-	-		otm3050
orthoMCL	1	0.900	-	-		OOG6_100199
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.730