DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycB and CYCB2;1

DIOPT Version :9

Sequence 1:	NP_726244.1	Gene:	CycB / 37618	FlyBaseID:	FBgn0000405	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_179353.1	Gene:	CYCB2;1 / 816269	AraportID:	AT2G17620	Length:	429	Species:	Arabidopsis thaliana

Alignment Length:	450	Identity:	136/450 - (30%)
Similarity:	196/450 - (43%)	Gaps:	91/450 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 NSVRNRV---PTKTT----------------------------------VEPTKVTVKSSSSENV 141
            ||..|::   ||.||                                  |.|..|..:.|...|.
plant     3 NSCENKIFVKPTSTTILQDETRSRKFGQEMKREKRRVLRVINQNLAGARVYPCVVNKRGSLLSNK 67

  Fly   142 NEPTLKREDSNLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRKEAETKKELPETKKDSLEVKKD 206
            .|     |:....||....||.::.:     ||:          |.||.|:|    |.|:....|
plant    68 QE-----EEEGCQKKKFDSLRPSVTR-----SGV----------EEETNKKL----KPSVPSAND 108

  Fly   207 ATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAG----------------IEDIDANDKENLVLVS 255
            ......|....|    |..:|..|||....:..                |.|||..|.:|.:...
plant   109 FGDCIFIDEEEA----TLDLPMPMSLEKPYIEADPMEEVEMEDVTVEEPIVDIDVLDSKNSLAAV 169

  Fly   256 EYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDR 320
            |||.|:|.:...:|....:..|::..|.:::.||||:||||:.|||.:|.|..||..|.|.:|||
plant   170 EYVQDLYAFYRTMERFSCVPVDYMMQQIDLNEKMRAILIDWLIEVHDKFDLINETLFLTVNLIDR 234

  Fly   321 YLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCN 385
            :|. .::..|..|||||:.||.:|.||||:..|.:.|.|.|:|..||...:.:||..:...:..|
plant   235 FLS-KQNVMRKKLQLVGLVALLLACKYEEVSVPVVEDLVLISDKAYTRNDVLEMEKTMLSTLQFN 298

  Fly   386 LSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHR 450
            :|.|....||:|:.|||.|:.:...::.:.||||.|:|||..:.||.:||.|::.:...|:|:
plant   299 ISLPTQYPFLKRFLKAAQADKKCEVLASFLIELALVEYEMLRFPPSLLAATSVYTAQCTLDGS-- 361

  Fly   451 AGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAKLARDAPQAKLKAIYNKYQGSKFQKIA 510
                   |.|..|..|:..||...|...:|.:..|.:.|....|..:|.||..|||..||
plant   362 -------RKWNSTCEFHCHYSEDQLMECSRKLVSLHQRAATGNLTGVYRKYSTSKFGYIA 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	Cyclin_N	260..387	CDD:278560	49/126 (39%)
CycB	NP_726244.1	Cyclin_C	389..515	CDD:281044	41/121 (34%)
CYCB2;1	NP_179353.1	Cyclin_N	174..300	CDD:278560	49/126 (39%)
CYCB2;1	NP_179353.1	Cyclin_C	302..419	CDD:281044	41/121 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I3347
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	193	1.000	Inparanoid score	I1359
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	1	1.000	-	-		FOG0000121
OrthoInspector	1	1.000	-	-		otm3050
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830