Protein Alignment CycB and CCND1

DIOPT Version :9

• Sequence 1: NP_726244.1
• Gene: CycB / 37618
• FlyBaseID: FBgn0000405
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_444284.1
• Gene: CCND1 / 595
• HGNCID: 1582
• Length: 295
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 65/252 - (25%)
• Similarity: 117/252 - (46%)
• Gaps: 40/252 - (15%)

  Fly   282 QKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATK 346
            ||||...||.::..|:.||..:.....|.|.||:..:||:|. ::..|::.|||:|.|.:|:|:|
Human    49 QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLS-LEPVKKSRLQLLGATCMFVASK 112

  Fly   347 YEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRY-SKAAGAEDEHHT 410
            .:|..|.........||::....::.||||.:...:..||:...|..|:..: ||...||:....
Human   113 MKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQI 177

  Fly   411 MSKY---FIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSA 472
            :.|:   |:.|.:.|.:..:..||.:||.|:..::.          |.|.|.....|::|.
Human   178 IRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQ----------GLNLRSPNNFLSYYR---- 228

  Fly   473 AHLRPITRLIAKLARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQSQR 529
                 :||.::::.:..|.. |:|...:.:               ||::|.:.|:|:
Human   229 -----LTRFLSRVIKCDPDC-LRACQEQIE---------------ALLESSLRQAQQ 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	Cyclin_N	260..387	CDD:278560	34/104 (33%)
		Cyclin_C	389..515	CDD:281044	25/129 (19%)
CCND1	NP_444284.1	CYCLIN_CCND1_rpt1	3..151	CDD:410276	33/102 (32%)
		CYCLIN_CCND1_rpt2	156..265	CDD:410279	30/144 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..295		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146277
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840