DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycB and ccnf

DIOPT Version :9

Sequence 1:	NP_726244.1	Gene:	CycB / 37618	FlyBaseID:	FBgn0000405	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	XP_012825809.1	Gene:	ccnf / 496496	XenbaseID:	XB-GENE-963729	Length:	764	Species:	Xenopus tropicalis

Alignment Length:	265	Identity:	71/265 - (26%)
Similarity:	128/265 - (48%)	Gaps:	27/265 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 SEYVNDIYDYLYQVELEQPIHKDHL-AGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAII 318
            ||.||.::      :...||:|..: ..||.::..||.:||||:.||......::....:.|.::
Frog   286 SELVNQVF------QSSLPINKTSIFTTQKGMNDTMRYILIDWLVEVATMKDFSSLCLHMTVGLV 344

  Fly   319 DRYLQVVKDTKRTYLQLVGVTALFIATKY--EELFPPAIGDFVFITDDTYTARQIRQMELQIFKA 381
            ||||: ::...|..|||||:..:.|.|::  :|:.  .|.:.|::||:||....:.:|..:|..|
Frog   345 DRYLK-LRSVPRAKLQLVGIACMVICTRFISKEIL--TIREAVWLTDNTYKYEDLVRMMGEIISA 406

  Fly   382 IDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLN 446
            ::..:..|..:.:....|.....:.....:..|..||:.:..|::||.|:::||.:|.|:..|
Frog   407 LEGKIRMPTVVDYKDVLSHLIPLDRSTLHLCSYISELSLLYTELSTYSPAQLAAGALLLARIL-- 469

  Fly   447 GNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAK--LARDAP----QAKLKAIYNKYQGSK 505
              |:..     |.|...|...:.::..||.|...|:.|  ...|||    |..|.|:..::|...
Frog   470 --HKQA-----RPWPAQLAETTGFTLEHLTPCVVLLHKKCFHDDAPKDYRQVSLTAVKQRFQDDL 527

  Fly   506 FQKIA 510
            :.:|:
Frog   528 YDQIS 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	Cyclin_N	260..387	CDD:278560	36/129 (28%)
CycB	NP_726244.1	Cyclin_C	389..515	CDD:281044	31/128 (24%)
ccnf	XP_012825809.1	FBOX	34..74	CDD:197608
		SLR repeat	87..111	CDD:276807
		Cyclin_N	301..412	CDD:365896	34/113 (30%)
		Cyclin_C	430..533	CDD:367282	29/112 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910