Protein Alignment CycB and CycB3

DIOPT Version :10

• Sequence 1: NP_726244.1
• Gene: CycB / 37618
• FlyBaseID: FBgn0000405
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: XP_312460.6
• Gene: CycB3 / 1273481
• VectorBaseID: AGAMI1_009615
• Length: 734
• Species: Anopheles gambiae
• Alignment Length: 705
• Identity: 171/705 - (24%)
• Similarity: 251/705 - (35%)
• Gaps: 220/705 - (31%)

  Fly     1 MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQN-------------------R 46
            ||.|..|.:.|              :::...|...||.|||:|.|                   .
Mosquito    39 MVETGTKRKAD--------------MSLAKQEIGAKRFALGNLTNAETTGTASTIGSVLKSKMTN 89

  Fly    47 GISRPIAAK-----DAAQ----------KDSKDLK-------LTDALRNAKARVDSHWKKQ---P 86
            .:|:|:.:.     |.|:          |.:|..|       :|.|....:..||.:.|.|   |
Mosquito    90 FLSKPMMSSNKLIGDVAKPTWKPNEQHFKKNKPPKIHGVPRIMTRAAMRKQQAVDVNQKTQQDRP 154

  Fly    87 LGSTNGNGNGAVPPKV-----NEGGVSAFLRSNS--------------VRNRVPTKTTVEPTKVT 132
            :....|..|  ||...     |..||||..:|..              |.||...|..:.....|
Mosquito   155 ISVMKGKEN--VPSSSDTVSGNVAGVSALAQSRKAEELVAKPKPLATVVTNRASWKNVLRARSTT 217

  Fly   133 VKSSSSENVNEPTLKREDSNLSKKSLTKLRAALA-------KPVMG--------------VSGI- 175
            |.:.:....|:.....|    .|||.....|.||       ||..|              |:.:
Mosquito   218 VATGAEIATNDSASNGE----QKKSQQAANACLAKHAEVVVKPKRGRMSSEFEASDNSLYVTAVD 278

  Fly   176 ----------------------------------RREPVAVSRK------------------EAE 188
                                              |.||...:.|                  |.|
Mosquito   279 NFEDGSAASAGTGPDCVDPLGPDCVDPLGPEIAPRNEPAPPAAKPLAARADVKPKQRGRGSSEFE 343

  Fly   189 TKKELPETKKDSLE----------------------------VKKDATRMP--------LIRGNS 217
            ....|..|..|:|:                            .||...|:.        ||..|.
Mosquito   344 DSGTLYMTAVDNLDDGATISNKGKAVAAAGRVATTGASLAAPDKKTKARVEDENGPWKMLITENV 408

  Fly   218 AVTTTTSTMPTTMSLSSKRL---AGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHL 279
            |:|..     .|..:...|.   |.:||.|.....::..||||..||:|||.:.|....| .|::
Mosquito   409 ALTRA-----ATAEIGVPRKQPPASVEDYDLCYWNDIYQVSEYAQDIFDYLQEREPAYDI-PDYM 467

  Fly   280 AGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIA 344
            ..||.::.:|||:|:||:.|:...|.|..||..|||.|:|.||..| ......|||||:..:.||
Mosquito   468 VRQKHLTKRMRALLVDWMIEIQETFELNHETLYLAVKILDTYLSRV-TIGHEVLQLVGIAGMLIA 531

  Fly   345 TKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHH 409
            :||:|..||.:.|||:..|..|....:.:||..:|:.|:.:|..||...|||||::.........
Mosquito   532 SKYDERLPPTVDDFVYFCDGAYDRNDLLKMERTVFRTIEFDLGFPLSYRFLRRYARVNRIPMMTL 596

  Fly   410 TMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAH 474
            |:::|.:|...:||.....|.|::|..:||::..:|:   :.|       |..||.:||.|.
Mosquito   597 TLARYILETGLMDYNTVLVRDSKLACGALFIARRMLD---QPG-------WNETLEYYSSYK--- 648

  Fly   475 LRPITRLIAKL--ARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQS 527
            :...|..|..|  ...:.|.....::.||....|.::|.|..:|.  |:.:...|
Mosquito   649 VEQFTDAIVLLNNGMSSRQYSFDTVHKKYSHELFFEVAKRPVITS--MEKLFATS 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	CYCLIN_CCNB1-like_rpt1	254..384	CDD:410211	54/129 (42%)
		CYCLIN_CCNB1-like_rpt2	389..509	CDD:410213	32/121 (26%)
CycB3	XP_312460.6	None