DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment blw and atpA

DIOPT Version :9

Sequence 1:	NP_726243.1	Gene:	blw / 37617	FlyBaseID:	FBgn0011211	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_051044.1	Gene:	atpA / 844790	-ID:	-	Length:	507	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	293/507 - (57%)
Similarity:	375/507 - (73%)	Gaps:	8/507 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 TQRSAEISNILEERILGVAPKADLEETGRVLSIGDGIARVYGLNNIQADEMVEFSSGLKGMALNL 108
            |.|:.|||||:.|||.....:..:..||.||.:||||||:|||:.:.|.|:|||..|..|:||||
plant     3 TIRADEISNIIRERIEQYNREVTIVNTGTVLQVGDGIARIYGLDEVMAGELVEFEEGTIGIALNL 67

  Fly   109 EPDNVGVVVFGNDKLIKQGDIVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGAINTKDRFRVGI 173
            |.:|||||:.|:..:|::|..||.||.|..:||.:..||||::||.|.|||:|.|:..:...:..
plant    68 ESNNVGVVLMGDGLMIQEGSSVKATGKIAQIPVSEAYLGRVINALANPIDGRGKISASESRLIES 132

  Fly   174 KAPGIIPRVSVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTALAIDTIINQKRFNEAQDES 238
            .|||||.|.||.||:|||:.|:||::||||||||||||||||||||:|.|||:||        :.
plant   133 PAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQ--------QG 189

  Fly   239 KKLYCIYVAIGQKRSTVAQIVKRLTDSGAMGYSVIVSATASDAAPLQYLAPYSGCAMGEYFRDKG 303
            :.:.|:|||||||.|:|||:|..|.:.|||.|:::|:.||...|.|||||||:|.|:.|||..:.
plant   190 QNVICVYVAIGQKASSVAQVVTSLQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRE 254

  Fly   304 KHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPAMGGGSLTALPV 368
            :|.|||||||||||.|||||||||||||||||||||||||||||||||||:|..:|.||:||||:
plant   255 QHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSQLGEGSMTALPI 319

  Fly   369 IETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGSMK 433
            :|||:|||||||||||||||||||||..:||..|||||||||:||||||||||.||||||||.:|
plant   320 VETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLK 384

  Fly   434 LELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAIEDQVAVIYCGVRGHLDKM 498
            |||||:.|:.||:||.||||.|||..|.||.||.|||||.|..|:.:|:|:..||.|..|:||.:
plant   385 LELAQFAELEAFSQFSSDLDKATQNQLARGQRLRELLKQSQSAPLTVEEQIMTIYTGTNGYLDGL 449

  Fly   499 DPAKITKFEKEFLQHIKTSEQALLDTIAKDGAISEASDAKLKDIVAKFMSTF 550
            :..::.||..:...::||::....:.||....::..:::.||:.:.:.:..|
plant   450 EIGQVRKFLVQLRTYLKTNKPQFQEIIASTKTLTAEAESFLKEGIQEQLERF 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blw	NP_726243.1	PRK09281	46..552	CDD:236448	292/505 (58%)
		ATP-synt_ab_N	68..134	CDD:280947	35/65 (54%)
		F1_ATPase_alpha	136..417	CDD:238552	185/280 (66%)
		ATP-synt_ab_C	426..520	CDD:278722	47/93 (51%)
atpA	NP_051044.1	atpA	23..507	CDD:176999	283/487 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54695
OrthoDB	1	1.010	-	-		D470054at2759
OrthoFinder	1	1.000	-	-		FOG0002237
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100771
Panther	1	1.100	-	-	O	PTHR48082
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1480
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930